Gastric secretion composed of all of the following Except:
- A. HCL.
- B. IF.
- C. Mucous.
- D. Amylase.
Correct Answer: D
Rationale: The correct answer is D: Amylase. Gastric secretion does not contain amylase. Amylase is an enzyme produced by the pancreas and salivary glands to break down carbohydrates. In the stomach, gastric secretions mainly consist of hydrochloric acid (HCl) for digestion, intrinsic factor (IF) for vitamin B12 absorption, and mucous to protect the stomach lining. Therefore, amylase is not a component of gastric secretion.
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Which statement about intestinal 'brakes' and 'accelerators' is FALSE?
- A. Dietary starch is a potent stimulator of small intestinal motility because it causes insulin release from the pancreas
- B. Food in the stomach causes gastrin release, which stimulates acid secretion
- C. Short-chain fatty acids which move from colon to caecum (reflux) promote ileo-caecal motility
- D. The arrival of lipid in the duodenum causes an immediate reduction in motility and a switch from the 'fasting' to the 'feeding' pattern.
Correct Answer: A
Rationale: The correct answer is A because dietary starch does not cause insulin release from the pancreas, but rather stimulates the release of incretin hormones like glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These incretins help regulate blood sugar levels postprandially and do not directly affect intestinal motility.
Incorrect choices:
B: Food in the stomach causing gastrin release is true and stimulates acid secretion.
C: Short-chain fatty acids moving from colon to caecum promoting ileo-caecal motility is true.
D: The arrival of lipid in the duodenum causing a reduction in motility is true.
What is the role of hydrochloric acid in the stomach?
- A. Break down carbohydrates
- B. Break down proteins
- C. Emulsify fats
- D. None of the above
Correct Answer: B
Rationale: The correct answer is B: Break down proteins. Hydrochloric acid in the stomach helps to activate pepsin, an enzyme that breaks down proteins into smaller peptides. This process is essential for proper digestion of proteins. Choice A is incorrect because carbohydrates are broken down by amylase enzymes in the mouth and small intestine. Choice C is incorrect because emulsification of fats occurs in the small intestine with the help of bile. Choice D is incorrect as hydrochloric acid plays a significant role in the digestion of proteins in the stomach.
Which of the following is a common risk factor for gallstones?
- A. High-fat diet
- B. Advanced age
- C. Gender (female)
- D. Family history of gallbladder disease
Correct Answer: C
Rationale: The correct answer is C: Gender (female). Women have a higher risk of developing gallstones due to hormonal factors, such as estrogen increasing cholesterol levels in bile. This imbalance can lead to gallstone formation. Advanced age (B) is a risk factor but not as common as gender. While a high-fat diet (A) can contribute to gallstone formation, it is not a primary risk factor. Family history (D) can increase the likelihood of gallstones, but it is not as common as being female.
Which of the following is synthesized and stored in the liver cells?
- A. Galactose
- B. Lactose
- C. Glycogen
- D. Arabinose
Correct Answer: C
Rationale: The correct answer is C: Glycogen. Glycogen is synthesized and stored in liver cells as a form of glucose storage for energy. The liver plays a key role in regulating blood glucose levels by converting excess glucose into glycogen for storage. Galactose (A) is a sugar found in milk and is metabolized in the liver, but it is not synthesized or stored there. Lactose (B) is a disaccharide found in dairy products and is broken down into glucose and galactose in the intestine, not synthesized or stored in the liver. Arabinose (D) is a sugar found in plants but is not synthesized or stored in the liver.
Which structure is located where the esophagus penetrates the diaphragm?
- A. esophageal hiatus
- B. cardiac orifice
- C. upper esophageal sphincter
- D. lower esophageal sphincter
Correct Answer: A
Rationale: The correct answer is A: esophageal hiatus. This is the opening in the diaphragm through which the esophagus passes, connecting the thoracic and abdominal cavities. The esophageal hiatus is specifically located at the level of the tenth thoracic vertebra. The other choices are incorrect because:
B: Cardiac orifice refers to the opening of the stomach into the esophagus, not where the esophagus penetrates the diaphragm.
C: Upper esophageal sphincter is a muscular valve at the upper end of the esophagus, not related to its passage through the diaphragm.
D: Lower esophageal sphincter is located at the junction of the esophagus and stomach, not at the point where the esophagus penetrates the diaphragm.