Nokea
Glucocorticoids causes:
- A. Protein catabolism and muscle atrophy
- B. Protein anabolism and increase of muscle mass
- C. Stimulation of growth in children
- D. Decrease of \mathrm{Na}+ reabsorbtion and \mathrm{K}+\mathrm{K}+ excretion
Correct Answer: A
Rationale: Glucocorticoids cause protein catabolism and muscle atrophy by breaking down proteins.
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Jim is being treated for hypertension. Because he has a history of heart attack, the drug chosen is atenolol. Beta blockers treat hypertension by:
- A. Increasing heart rate to improve cardiac output
- B. Reducing vascular smooth muscle tone
- C. Increasing aldosterone-mediated volume activity
- D. Reducing aqueous humor production
Correct Answer: B
Rationale: Beta blockers like atenolol reduce vascular tone and heart rate, lowering blood pressure.
A nurse is providing discharge instructions for a client who has a new prescription for an antihypertensive medication. Which of the following statements should the nurse give?
- A. Be sure to limit your potassium intake while taking the medication.
- B. You should check your blood pressure every 8 hours while taking this medication.
- C. Your medication dosage will be increased if you develop tachycardia.
- D. Change positions slowly when you move from sitting to standing.
Correct Answer: D
Rationale: Antihypertensives can cause orthostatic hypotension; changing positions slowly prevents dizziness or falls.
Only free drugs can act on target sites and can be eliminated.
- A. TRUE
- B. FALSE
Correct Answer: A
Rationale: True; only free (unbound) drugs can interact with target sites and be filtered/excreted, as bound drugs are pharmacologically inactive.
When using the nursing process in medication therapy, what does it ensure?
- A. That medications are given at the right time
- B. That there is efficient and effective care
- C. That the right dose of the drug is given to the patient
- D. The right drug is given to the right patient at the right time
Correct Answer: B
Rationale: The nursing process ensures efficient and effective care by systematically addressing all aspects of medication therapy.
Which cytochrome is responsible for drug metabolism?
- A. P-450
- B. C-3b
- C. C-3a
- D. C-2a
Correct Answer: A
Rationale: Cytochrome P-450 enzymes in the liver are primary for drug metabolism.