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Herpes simplex infections on lips and in the mouth are most commonly caused by:

  • A. HSV-1
  • B. HSV-2
  • C. HSV-6
  • D. HSV-7
Correct Answer: A

Rationale: The correct answer is A: HSV-1. Herpes simplex infections on lips and in the mouth are most commonly caused by HSV-1 due to its preference for infecting oral mucosa. HSV-2 typically causes genital herpes. HSV-6 and HSV-7 are less common and not typically associated with oral infections. Therefore, based on the typical presentation and epidemiology of herpes simplex infections, HSV-1 is the most likely cause in this scenario.