Nokea
In childhood asthma:
- A. Over 90% of patients show exercise-induced bronchoconstriction
- B. Hypercapnia is the first physiological disturbance in status asthmaticus
- C. Infants are unresponsive to bronchodilators
- D. Spontaneous cure occurs before adolescence
Correct Answer: D
Rationale: Spontaneous cure before adolescence is a recognized phenomenon in childhood asthma, though not all cases resolve. Other options are incorrect: exercise-induced bronchoconstriction is common but not universal, hypercapnia occurs late in status asthmaticus, and infants do respond to bronchodilators.
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All of the following are minor criteria in the latest Revised Jones criteria for rheumatic fever in moderate-high risk population except
- A. Monoarthalgia
- B. Fever with body temperature ≥ 38.5°C
- C. ESR 230 mm/hour
- D. Prolonged PR interval
Correct Answer: C
Rationale: ESR 230 mm/hour is not a minor criterion in the Revised Jones criteria for rheumatic fever.
Pulmonary stenosis
- A. Most common at pulmonary valve level
- B. Valve dilatation done for dysplastic valves
- C. Ejection click occurs in past stenotic dilatation
- D. Surgery done when Rt ventricular pressure exceeds 25 mmHg
Correct Answer: A
Rationale: Pulmonary stenosis is most commonly found at the pulmonary valve level.
The enzyme producing carbon monoxide within the human body is
- A. Aminolevulinic acid synthase
- B. Heme oxygenase
- C. Cyclo-oxygense
- D. Nitric oxide synthase
Correct Answer: B
Rationale: Heme oxygenase is responsible for the production of carbon monoxide during the breakdown of heme.
Progressive spinal muscular atrophy of infancy presents with:
- A. Severe generalised weakness
- B. Fasciculations in the tongue
- C. Loss of spinothalamic tract function
- D. Spontaneous fibrillation on electromyography
Correct Answer: A
Rationale: Progressive spinal muscular atrophy presents with severe weakness and tongue fasciculations. Spinothalamic tract function is preserved, and electromyography shows fibrillation.
Medical treatment of myasthenia gravis includes:
- A. Thymectomy
- B. Physostigmine
- C. Edrophonium
- D. Anticholinergic agents
Correct Answer: C
Rationale: Edrophonium: Edrophonium is used in the diagnosis and short-term treatment of myasthenia gravis as it improves neuromuscular transmission by inhibiting acetylcholinesterase.