In choosing a benzodiazepam to treat anxiety the prescriber needs to be aware of the possibility of dependence. The benzodiazepam with the greatest likelihood of rapidly developing dependence is:
- A. Chlordiazepoxide (Librium)
- B. Clonazepam (Klonopin)
- C. Alprazolam (Xanax)
- D. Oxazepam (Serax)
Correct Answer: C
Rationale: Alprazolam's short half-life increases dependence risk.
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Jim is being treated for hypertension. Because he has a history of heart attack, the drug chosen is atenolol. Beta blockers treat hypertension by:
- A. Increasing heart rate to improve cardiac output
- B. Reducing vascular smooth muscle tone
- C. Increasing aldosterone-mediated volume activity
- D. Reducing aqueous humor production
Correct Answer: B
Rationale: Beta blockers like atenolol reduce vascular tone and heart rate, lowering blood pressure.
Which of the following is true about procainamide and its dosing schedule?
- A. It produces bradycardia and should be used cautiously in patients with cardiac conditions that a slower heart rate might worsen.
- B. Gastrointestinal adverse effects are common so the drug should be taken with food.
- C. Adherence can be improved by using a sustained release formulation that can be given once daily.
- D. Doses of this drug should be taken evenly spaced around the clock to keep an even blood level.
Correct Answer: D
Rationale: Even spacing maintains steady procainamide levels.
Inhaled corticosteroids in Bronchial Asthma:
- A. Produce modest immediate bronchodilation
- B. Are synergistic with inhaled methacholine
- C. Are antagonized by atropine
- D. Inhibit IgE-antigen binding
Correct Answer: D
Rationale: Inhaled corticosteroids reduce inflammation by inhibiting IgE-mediated responses.
The first-line treatment for cough related to an upper respiratory tract infection (URI) in a 5-year-old child is:
- A. Fluids and symptomatic care
- B. Dextromethorphan and guaifenesin syrup (Robitussin DM for Kids)
- C. Guaifenesin and codeine syrup (Tussin AC)
- D. Chlorpheniramine and dextromethorphan syrup (Nyquil for Kids)
Correct Answer: A
Rationale: Fluids and symptomatic care are safest and recommended for URI cough in young children; cough suppressants are discouraged under 6.
Symptoms of folate deficiency include:
- A. Thinning of the hair
- B. Bruising easily
- C. Glossitis
- D. Numbness and tingling of the hands and feet
Correct Answer: C
Rationale: Glossitis (inflamed tongue) is a classic symptom of folate deficiency.
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