Nokea
In deciding which of multiple drugs used to use to treat a condition, the NP chooses Drug A because it:
- A. Has serious side effects and it is not being used for a life-threatening condition
- B. Will be taken twice daily and will be taken at home
- C. Is expensive, but covered by health insurance
- D. None of these are important in choosing a drug
Correct Answer: B
Rationale: Choosing a drug taken twice daily at home reflects practical considerations like adherence, outweighing side effects or cost alone . All factors matter (D is false).
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Which of the following is biguanide:
- A. Glibenclamide
- B. Metformin
- C. Acarbose
- D. Liraglutide
Correct Answer: B
Rationale: Metformin is a biguanide that reduces hepatic glucose output.
Attenuated vaccines are also known as:
- A. Killed vaccines
- B. Booster vaccines
- C. Inactivated vaccines
- D. Live vaccines
Correct Answer: D
Rationale: Attenuated vaccines are live, weakened forms, unlike killed/inactivated or booster-specific vaccines.
A client is taking Humulin NPH insulin daily every morning. The nurse reinforces instructions for the client and tells the client that the most likely time for a hypoglycemic reaction to occur is:
- A. 2 to 4 hours after administration
- B. 4 to 12 hours after administration
- C. 16 to 18 hours after administration
- D. 18 to 24 hours after administration
Correct Answer: B
Rationale: Humulin NPH is an intermediate-acting insulin. The onset of action is 1.5 hours, it peaks in 4 to 12 hours, and its duration of action is 24 hours. Hypoglycemic reactions most likely occur during peak time.
A nurse is teaching a client who has a new prescription for Nitroglycerin transdermal patch for Angina Pectoris. Which of the following instructions should the nurse include?
- A. Remove the patch each evening.
- B. Cut each patch in half if angina attacks are under control.
- C. Take off the nitroglycerin patch for 30 min if a headache occurs.
- D. Apply a new patch every 48 hr
Correct Answer: A
Rationale: Removing the patch nightly prevents tolerance to nitroglycerin.
Which statement accurately describes a drug agonist?
- A. A drug that reacts with specific receptor sites on a cell and prevents the reaction of another chemical with a different receptor site on that cell
- B. A drug that interferes with the enzyme systems that act as catalysts for different chemical reactions
- C. A drug that interacts directly with receptor sites to cause the same activity that a natural chemical would cause at that site
- D. A drug that reacts with receptor sites to block normal stimulation, producing no effect
Correct Answer: C
Rationale: Agonists are drugs that produce effects similar to those produced by naturally occurring neurotransmitters, hormones, or other substances found in the body. Noncompetitive antagonists are drugs that react with certain receptor sites, preventing the reaction of another chemical with a different receptor site. Drug-enzyme interactions interfere with the enzyme systems that stimulate various chemical reactions.