Nokea
The typical response to intravenous injection of 5-HT in an anaesthetised animal is:
- A. Rise in BP
- B. Fall in BP
- C. Rise followed by brief fall in BP
- D. Sharp fall, followed by brief rise, followed by prolonged fall in BP
Correct Answer: D
Rationale: IV 5-HT (serotonin) typically causes a triphasic BP response in anesthetized animals: an initial sharp fall (vasodilation), a brief rise (vasoconstriction), and a prolonged fall (Bezold-Jarisch reflex).
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Which is not an antithyroid drug?
- A. Mercazolile
- B. Triiodthyronine
- C. Diiodthyrosine
- D. Potassium iodade
Correct Answer: B
Rationale: Triiodothyronine (T3) is a thyroid hormone, not an antithyroid drug, unlike the others which inhibit thyroid function.
Prior to administering a prescribed drug, the nurse correctly identifies the client by which method?
- A. Checking a client's name on his or her wristband
- B. Checking a client's chart
- C. Asking the client if the are Mr. Jones
- D. Asking a client if he or she is the correct client
Correct Answer: A
Rationale: Client identifiers can include visual and verbal methods. Visual methods include use of a recent picture of the client or client wristband. Verbal methods include asking the client for his or her name and another unique identifier, such as his or her birth date. Never ask a client, 'Are you Mr. Jones?' because some clients may respond by answering 'yes' even though that is not their name due to confusion or difficulty hearing. Checking the client's chart would be inappropriate to use for identifying the client.
The nurse is teaching a patient who has completed detoxification for alcohol abuse who will be discharged home with a prescription for disulfiram (Antabuse). Which statement by the patient indicates understanding of the teaching?
- A. Even topical products containing alcohol can have serious adverse effects while I am taking this drug
- B. If I experience drowsiness or skin rash, I should discontinue this drug immediately
- C. It is safe to take a product containing alcohol one week after the last dose of disulfiram
- D. This drug acts by blocking the pleasurable effects of alcohol
Correct Answer: A
Rationale: Disulfiram reacts with any alcohol, even topical; effects linger 2 weeks , and it causes aversion, not blocking pleasure . Disulfiram causes an unpleasant and potentially fatal reaction if alcohol is consumed while taking it and can even occur with topical products containing alcohol.
Which of the following is biguanide:
- A. Glibenclamide
- B. Metformin
- C. Acarbose
- D. Liraglutide
Correct Answer: B
Rationale: Metformin is a biguanide that reduces hepatic glucose output.
The following drugs can be used for treatment of diabetes except one:
- A. Insulines
- B. Biguanides
- C. alfa glucosidase inhibitors
- D. Glucagon
Correct Answer: D
Rationale: Glucagon increases blood glucose levels by promoting glycogenolysis and gluconeogenesis, making it unsuitable for diabetes treatment, unlike the others which lower glucose.