Burns Pediatric Primary Care 7th Edition Test Bank Related

Review Burns Pediatric Primary Care 7th Edition Test Bank related questions and content

In JRA, the autoimmune reaction primarily occurs in the:

  • A. joint tendons.
  • B. cartilage.
  • C. synovial tissue.
  • D. interstitial space.
Correct Answer: C

Rationale: In Juvenile Rheumatoid Arthritis (JRA), which is now referred to as Juvenile Idiopathic Arthritis (JIA), the autoimmune reaction primarily occurs in the synovial tissue of the joints. The synovial tissue lines the inside of the joint capsule and produces synovial fluid, which helps to lubricate and nourish the joint. In JIA, the immune system mistakenly targets the synovial tissue, leading to inflammation, pain, and damage to the joints. This inflammatory process can result in swelling, warmth, stiffness, and eventual joint destruction if left untreated. Therefore, the synovial tissue is the primary site of the autoimmune reaction in JRA/JIA.