Nokea
In order to prevent wound infection associated with surgical procedures a patient was given a synthetic antiprotozoan drug with a high activity against Helicobacter pylori. Specify this drug:
- A. Metronidazole
- B. Doxycycline hydrochloride
- C. Chingamin
- D. Acyclovir
Correct Answer: A
Rationale: The correct answer is A: Metronidazole. Metronidazole is a synthetic antiprotozoan drug with high activity against Helicobacter pylori, a bacterium that can cause wound infections. Metronidazole specifically targets anaerobic bacteria like H. pylori, making it effective in preventing wound infections.
Incorrect choices:
B: Doxycycline hydrochloride - Doxycycline is primarily used for bacterial infections, not protozoan infections like H. pylori.
C: Chingamin - Chingamin is not a commonly used drug for treating H. pylori infections or preventing wound infections.
D: Acyclovir - Acyclovir is an antiviral drug used to treat herpes infections, not bacterial or protozoan infections like H. pylori.
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A patient who has been taking tetracycline for a long time has developed candidosis of mucous membranes. What drug shoul administered for its treatment?
- A. Itraconazole
- B. Griseofulvin
- C. Nitrofungin
- D. Amphotericin
Correct Answer: A
Rationale: The correct answer is A: Itraconazole. Itraconazole is an antifungal medication commonly used to treat candidosis. It works by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes. This action disrupts the integrity of the fungal cell membrane, leading to cell death. Griseofulvin (B) is primarily used to treat fungal infections of the skin and nails, not mucous membranes. Nitrofungin (C) is not commonly used for candidosis treatment. Amphotericin (D) is a potent antifungal medication but is typically reserved for severe or systemic fungal infections due to its potential side effects.
Which fact is correct about the nucleoids in bacteria:
- A. Contain a haploid bacterial chromosomes in each nucleus
- B. Are reabsorbed well by the method of Neisser
- C. Are 1 to 4 in each bacterial cell depending on the nature of the cell and the phases of growth and replication
- D. None of the above
Correct Answer: C
Rationale: The correct answer is C because nucleoids in bacteria can vary in number from 1 to 4 depending on the specific bacterial cell and its growth and replication phases. This is due to the dynamic nature of bacterial cells and their genetic material organization.
Choice A is incorrect because nucleoids do not contain nuclear membranes or multiple haploid chromosomes like eukaryotic nuclei. Choice B is incorrect as there is no known method of reabsorbing nucleoids by Neisser. Choice D is incorrect as option C is indeed the correct statement regarding the number of nucleoids in bacterial cells.
Which form of human plague is present with high fever and large lymphadenopathies (buboes). The case fatality in untreated cases may reach 60%.
- A. Bubonic plague
- B. Pneumonic plague
- C. Gastrointestinal plague
- D. Septicemic plague
Correct Answer: A
Rationale: The correct answer is A: Bubonic plague. Bubonic plague is characterized by high fever and large swollen lymph nodes (buboes). The case fatality rate in untreated cases can reach 60%. This form of plague is typically transmitted through the bite of an infected flea.
B: Pneumonic plague presents with respiratory symptoms and is transmitted through respiratory droplets.
C: Gastrointestinal plague is not a recognized form of plague.
D: Septicemic plague is a severe form of plague where the bacteria multiply in the bloodstream. It may not always present with buboes.
A child with diarrhea had stool microscopy revealing cysts with four nuclei. What is the most likely causative agent?
- A. Entamoeba histolytica
- B. Giardia lamblia
- C. Balantidium coli
- D. Trichomonas hominis
Correct Answer: A
Rationale: The correct answer is A: Entamoeba histolytica. This pathogen is known to cause amoebic dysentery, characterized by diarrhea with bloody or mucoid stools. The presence of cysts with four nuclei in the stool microscopy is a characteristic feature of Entamoeba histolytica. Other choices are incorrect because Giardia lamblia typically presents with binucleate cysts, Balantidium coli is a ciliated protozoan, and Trichomonas hominis is a non-pathogenic parasite found in the human intestine.
Microscopy of a smear obtained from a patient with acute purulent periostitis revealed gram-positive bacteria arranged in clusters resembling bunch of grapes. What microorganisms is this morphology typical for?
- A. Staphylococci
- B. Sarcina
- C. Tetracocci
- D. Candida fungi
Correct Answer: A
Rationale: Rationale:
Staphylococci are gram-positive bacteria that typically arrange in clusters resembling a bunch of grapes. This characteristic morphology is specific to staphylococci due to their division pattern. Sarcina, Tetracocci, and Candida fungi do not exhibit this clustering pattern. Staphylococci are commonly associated with purulent infections, making them the most likely microorganisms in this scenario.