Hematologic System Assessment Questions Related

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In which of the following conditions is percent transferrin iron saturation highest?

  • A. Anemia of chronic disease
  • B. Iron deficiency
  • C. Pernicious anemia
  • D. Hemachromatosis
Correct Answer: D

Rationale: The correct answer is D: Hemachromatosis. In hemachromatosis, the body absorbs and stores too much iron, leading to high transferrin iron saturation.

Rationale:
1. In hemachromatosis, the body absorbs excess iron from the diet, causing high iron levels in the blood.
2. Transferrin is a protein that transports iron in the blood. In hemachromatosis, the high iron levels saturate the transferrin, leading to high percent transferrin iron saturation.
3. Anemia of chronic disease (A) is characterized by low iron levels and low transferrin iron saturation.
4. Iron deficiency (B) results in low iron levels and low transferrin iron saturation.
5. Pernicious anemia (C) is caused by vitamin B12 deficiency, not iron overload, leading to normal to low transferrin iron saturation.

Summary: Hemachromatosis leads to high