Nokea
In Wilson's disease:
- A. There is an association with high caeruloplasmin levels
- B. Hepatic copper deposition is pathognomonic
- C. There is increased urinary excretion of copper
- D. There are copper deposits on the cornea
Correct Answer: D
Rationale: Copper deposits on the cornea (Kayser-Fleischer rings) are a hallmark of Wilson's disease, a genetic disorder leading to copper accumulation in tissues.
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Emergency management of acute asthma includes:
- A. Arterial blood gas
- B. Nebulised steroids
- C. Intravenous theophylline
- D. Nebulised ~-antagonists
Correct Answer: D
Rationale: Nebulised beta-antagonists are a key part of the emergency management of acute asthma. Arterial blood gas, nebulised steroids, and intravenous theophylline are also used but are not the first line.
What is cardiac power output (CPO) in a patient with acute anterior wall ST-elevation myocardial infarction and left ventricular failure? His mean arterial pressure was 60 mm Hg and cardiac output calculated on echo was 2.91l min−1.
- A. 0.48
- B. 0.38
- C. 0.58
- D. 0.68
Correct Answer: C
Rationale: Cardiac power output is calculated as (MAP × cardiac output) / 451. For the given values, the correct calculation gives a value of 0.58.
Which of the following has the highest proportion of etiology of congenital malformations?
- A. Maternal infections
- B. Maternal illness
- C. Environmental agents
- D. Monogenic inheritance
Correct Answer: D
Rationale: Monogenic inheritance accounts for the highest proportion of congenital malformations.
The severity of symptoms of Ebstein anomaly and the degree of cyanosis are high and depend on the extent of
- A. displacement of the tricuspid valve
- B. cardiac dysrhythmias
- C. atrial right-to-left shunt
- D. pulmonary vascular resistance
Correct Answer: A
Rationale: Displacement of the tricuspid valve is a key determinant of symptom severity in Ebstein anomaly.
Developmental delay in children below 3 years of age is defined as
- A. 25% departure from typical performance in 2 developmental domains
- B. 25% departure from typical performance in any developmental domain
- C. 30% departure from typical performance in ≥2 developmental domains
- D. 30% departure from typical performance in any developmental domain
Correct Answer: D
Rationale: Developmental delay in children below 3 years is defined as a 30% departure from typical performance in any developmental domain, indicating significant lag.