Nokea
Inhaled corticosteroids in Bronchial Asthma:
- A. Produce modest immediate bronchodilation
- B. Are synergistic with inhaled methacholine
- C. Are antagonized by atropine
- D. Inhibit IgE-antigen binding
Correct Answer: D
Rationale: Inhaled corticosteroids reduce inflammation by inhibiting IgE-mediated responses.
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A pharmacology student asks the instructor what an accurate description of a drug agonist is. What is the instructors best response?
- A. A drug that reacts with a receptor site on a cell preventing a reaction with another chemical on a different receptor site
- B. A drug that interferes with the enzyme systems that act as catalyst for different chemical reactions
- C. A drug that interacts directly with receptor sites to cause the same activity that a natural chemical would cause at that site
- D. A drug that reacts with receptor sites to block normal stimulation, producing no effect
Correct Answer: C
Rationale: Agonists are drugs that produce effects similar to those produced by naturally occurring neurotransmitters, hormones, or other substances found in the body. Noncompetitive antagonists are drugs that react with some receptor sites preventing the reaction of another chemical with a different receptor site. Drug-enzyme interactions interfere with the enzyme systems that stimulate various chemical reactions.
A nurse is teaching the parents of a school-age child about transdermal Methylphenidate. Which of the following instructions should the nurse include?
- A. Apply one patch twice per day.
- B. Leave the patch on for 9 hr.
- C. Apply the patch to the child's waist.
- D. Use opened tray within 6 months.
Correct Answer: B
Rationale: Methylphenidate patches are worn for 9 hours to control ADHD symptoms during the day.
The client has a PRN prescription for loperamide hydrochloride (Imodium). The nurse understands that this medication is used for which condition?
- A. Constipation
- B. Abdominal pain
- C. An episode of diarrhea
- D. Hematest-positive nasogastric tube drainage
Correct Answer: C
Rationale: Loperamide is an antidiarrheal agent. It is used to manage acute and also chronic diarrhea in conditions such as inflammatory16inflammatory bowel disease. Loperamide also can be used to reduce the volume of drainage from an ileostomy. It is not used for the conditions in options 1, 2, and 4.
The burn client is receiving treatments of topical mafenide acetate (Sulfamylon) to the site of injury. The nurse monitors the client, knowing that which of the following indicates that a systemic effect has occurred?
- A. Hyperventilation
- B. Elevated blood pressure
- C. Local pain at the burn site
- D. Local rash at the burn site
Correct Answer: A
Rationale: Mafenide acetate is a carbonic anhydrase inhibitor and can suppress renal excretion of acid, thereby causing acidosis. Clients receiving this treatment should be monitored for signs of an acid-base imbalance (hyperventilation). If this occurs, the medication should be discontinued for 1 to 2 days. Options 3 and 4 describe local rather than systemic effects. An elevated blood pressure may be expected from the pain that occurs with a burn injury.
The trial period to determine effective anti-inflammatory activity when starting a patient on aspirin for rheumatoid arthritis is:
- A. 48 hours
- B. 4 to 6 days
- C. 4 weeks
- D. 2 months
Correct Answer: B
Rationale: Aspirin's anti-inflammatory effect for RA takes 4-6 days; 48 hours is too short.