Nokea
Ipratropium bromide is
- A. Bronchoselective anticholinergic
- B. Used as mydriatic
- C. A selective MI anticholinergic useful in peptic ulcer
- D. An antiparkinsonism drug
Correct Answer: A
Rationale: Ipratropium is a bronchoselective anticholinergic used in COPD/asthma.
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Patient education regarding taking iron replacements includes:
- A. Doubling the dose if they miss a dose to maintain therapeutic levels
- B. Taking the iron with milk or crackers if it upsets their stomach
- C. Iron is best taken on an empty stomach with juice
- D. Antacids such as Tums may help the upset stomach caused by iron therapy
Correct Answer: C
Rationale: Iron absorption is best on an empty stomach with juice; milk or antacids reduce absorption, and doubling risks toxicity.
In post menopausal women who are receiving estrogen replacement therapy, medroxyprogesterone is administered concurrently to reduce the risk of:
- A. Atherosclerosis
- B. Endometrial cancer
- C. Hypertension
- D. Osteoporosis
Correct Answer: B
Rationale: Progestins like medroxyprogesterone reduce estrogen-induced endometrial hyperplasia and cancer risk.
Laboratory monitoring for patients on angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers should include:
- A. White blood cell counts with the drug dosage increased for elevations above 10,000 feet
- B. Liver function tests with the drug dosage stopped for alanine aminotransferase values twice that of normal
- C. Serum creatinine levels with the drug dosage reduced for values greater than 2.5 mg/dL
- D. Serum glucose levels with the drug dosage increased for levels greater than 120 mg/dL
Correct Answer: C
Rationale: Elevated creatinine (>2.5 mg/dL) indicates renal impairment, requiring dose adjustment.
The patient is taking a 2-mg dose of ropinerol XR. The drug has a half-life of 12 hours. How long will it be before only 0.25 mg of this drug remains in the patient's system?
- A. 24 hours
- B. 36 hours
- C. 48 hours
- D. 60 hours
Correct Answer: B
Rationale: The half-life of a drug is the time it takes for the amount of drug in the body to decrease to half of the peak level it previously achieved. At 12 hours there will be 1 mg of the drug available to the body. At 24 hours there will be 0.5 mg, at 36 hours there will be 0.25 mg, at 48 hours there will be 0.125 mg, and at 60 hours there will be 0.0625 mg.
Flushing occurs when alcohol is taken along with
- A. Phenformin
- B. Chlorpropamide
- C. Glibenclamide
- D. Tolbutamide
Correct Answer: B
Rationale: Chlorpropamide causes a disulfiram-like reaction with alcohol, leading to flushing.