Nokea
The study of dose, distribution, metabolism & excretion of drugs in the body is known as
- A. Pharmacognosia
- B. Pharmacodynamics
- C. Dose effective study
- D. Pharmacotherapy
Correct Answer: B
Rationale: Pharmacodynamics studies drug effects, but pharmacokinetics (dose, distribution, metabolism, excretion) is more specific here; likely a typo in the document.
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The patient is taking a 2-mg dose of ropinerol XR. The drug has a half-life of 12 hours. How long will it be before only 0.25 mg of this drug remains in the patient's system?
- A. 24 hours
- B. 36 hours
- C. 48 hours
- D. 60 hours
Correct Answer: B
Rationale: The half-life of a drug is the time it takes for the amount of drug in the body to decrease to half of the peak level it previously achieved. At 12 hours there will be 1 mg of the drug available to the body. At 24 hours there will be 0.5 mg, at 36 hours there will be 0.25 mg, at 48 hours there will be 0.125 mg, and at 60 hours there will be 0.0625 mg.
Patients whose total dose of prednisone will exceed 1 gram will most likely need a second prescription for:
- A. Metformin, a biguanide to prevent diabetes
- B. Omeprazole, a proton pump inhibitor to prevent peptic ulcer disease
- C. Naproxen, an NSAID to treat joint pain
- D. Furosemide, a diuretic to treat fluid retention
Correct Answer: B
Rationale: High-dose prednisone risks ulcers, warranting omeprazole; diabetes or fluid are less immediate.
A home care nurse visits a client recently diagnosed with diabetes mellitus who is taking Humulin NPH insulin daily. The client asks the nurse how to store the unopened vials of insulin. The nurse tells the client to:
- A. Freeze the insulin.
- B. Refrigerate the insulin.
- C. Store the insulin in a dark, dry place.
- D. Keep the insulin at room temperature.
Correct Answer: B
Rationale: Insulin in unopened vials should be stored under refrigeration until needed. Vials should not be frozen. When stored unopened under refrigeration, insulin can be used up to the expiration date on the vial. Options 1, 3, and 4 are incorrect.
When moving to another state, what is the nurse responsible for becoming familiar with?
- A. Local policies and procedures for controlled substance administration
- B. Local provider's Drug Enforcement Agency (DEA) number for prescribing controlled substances
- C. The agency monitoring controlled substances in the new state
- D. Board of Nursing regulations of controlled substances in the new state
Correct Answer: A
Rationale: The nurse needs to learn local policies and procedures for controlled substance administration because they can vary with some local governments more rigorous than others. Nurses do not memorize a provider's DEA numbers. The DEA is a federal agency that monitors controlled substances in all states. State boards of nursing do not regulate controlled substances but may regulate how controlled substances are administered by nurses.
The standard dosage of St John's wort for the treatment of mild depression is:
- A. 300 mg daily
- B. 100 mg three times a day
- C. 300 mg three times a day
- D. 600 mg three times a day
Correct Answer: C
Rationale: 300 mg three times daily is the standard dose for St John's wort in mild depression.