Nokea
Which of the following antiarrhythmic agents has the longest plasma half-life?
- A. Amiodarone
- B. Disopyramide
- C. Quinidine
- D. Disopyramide
Correct Answer: A
Rationale: Amiodarone has a half-life of weeks due to extensive tissue distribution.
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Which of the following is an adverse event of glucocorticoids:
- A. Arterial hypotension
- B. Hyponatremia
- C. Hypoglicemia
- D. Facilitate the development of infections
Correct Answer: D
Rationale: Glucocorticoids suppress immunity, increasing infection risk due to reduced inflammatory and immune responses.
The nurse applies the nursing process in medication therapy to ensure what?
- A. That medications are given at the right time
- B. That care is efficient and effective
- C. That the right dose of the drug is given to the patient
- D. That the right drug is given to the right patient at the right time
Correct Answer: B
Rationale: The nursing process ensures efficient, effective care, encompassing all aspects of safe administration.
A patient's liquid cough medicine has been discontinued with one half of the bottle remaining. The home health nurse is aware that according to the U.S. Food and Drug Administration (FDA) guidelines on prescription medication disposal, the next step should be to:
- A. save the remainder for another patient with the same prescription.
- B. flush the remainder down the toilet.
- C. read the drug label for specific disposal instructions.
- D. pour remaining medication into a hazardous waste container.
Correct Answer: C
Rationale: The nurse must follow specific disposal instructions on the drug label or in the patient information leaflet that accompanies the medication. Prescription medications should not be shared among patients. Prescription drugs should not be flushed down the toilet unless specifically instructed to do so by the manufacturer. The first action to be taken is to follow disposal instructions on the label. If the drug label indicates it should be emptied into a hazardous waste container, measures should be taken to prevent leaking and/or accidental ingestion.
All of the following statements about efficacy and potency are true EXCEPT:
- A. Efficacy is usually a more important clinical consideration than potency
- B. Efficacy is the maximum effect of a drug
- C. Potency is a comparative measure, refers to the different doses of two drugs that are needed to produce the same effect
- D. The ED50 is a measure of drug's efficacy
Correct Answer: D
Rationale: ED50 measures potency (dose for 50% effect), not efficacy (maximal effect).
The elderly are at high risk of ADRs due to:
- A. Having greater muscle mass than younger adults, leading to higher volume of distribution
- B. The extensive studies that have been conducted on drug safety in this age group
- C. The blood-brain barrier being less permeable, requiring higher doses to achieve therapeutic effect
- D. Age-related decrease in renal function
Correct Answer: D
Rationale: Age-related renal decline slows drug clearance, raising ADR risk in the elderly, unlike muscle mass , studies , or BBB .