Irreversible interaction of an antagonist with a receptor is due to:
- A. Ionic bonds
- B. Hydrogen bonds
- C. Covalent bonds
- D. All of the above
Correct Answer: C
Rationale: Irreversible antagonism typically involves covalent bonding, making it permanent.
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Which of the following statement is not correct for insulin medications:
- A. Effective for treatment of diabetes type I
- B. Effective for treament of diabetes type II
- C. Is for parenteral use
- D. Is for intravenous use only
Correct Answer: D
Rationale: Insulin is not exclusively for IV use; it's typically subcutaneous, though IV is used in emergencies.
A potentially life-threatening adverse response to angiotensin-converting enzyme inhibitors is angioedema. Which of the following statements is true about this adverse response?
- A. Swelling of the tongue or hoarseness are the most common symptoms.
- B. It appears to be related to the decrease in aldosterone production.
- C. Presence of a dry, hacky cough indicates a high risk for this adverse response.
- D. Because it takes time to build up a blood level, it occurs after being on the drug for about 1 week.
Correct Answer: A
Rationale: Angioedema presents with tongue swelling or hoarseness and is not linked to cough or aldosterone.
A nurse is teaching a client about preventing Otitis Externa. Which of the following instructions should the nurse include?
- A. Clean the ear with a cotton-tipped swab daily
- B. Place earplugs in the ears when sleeping at night.
- C. Use a cool water irrigation solution to remove earwax.
- D. Tip the head to the side to remove water from the ears after showering
Correct Answer: D
Rationale: Tipping the head removes water, preventing moisture that promotes otitis externa.
Digoxin levels need to be monitored closely when the following medication is started:
- A. Loratadine
- B. Diphenhydramine
- C. Ipratropium
- D. Albuterol
Correct Answer: D
Rationale: Albuterol , a beta-agonist, can increase digoxin levels by enhancing its effects, requiring close monitoring; antihistamines and ipratropium have minimal impact.
Phenytoin decreases folic acid absorption by:
- A. Altering the pH of the stomach
- B. Increasing gastric emptying time
- C. Inhibiting intestinal enzymes required for folic acid absorption
- D. Chelation of the folic acid into inactive ingredients
Correct Answer: C
Rationale: Phenytoin inhibits intestinal conjugase enzymes, reducing folic acid absorption.
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