Nokea
Lispro is an insulin analogue produced by recombinant DNA technology. Which of the following statements about this form of insulin is NOT true?
- A. Optimal time of preprandial injection is 15 minutes
- B. Duration of action is increased when the dose is increased
- C. It is compatible with neutral protamine Hagedorn insulin
- D. It has no pronounced peak
Correct Answer: B
Rationale: Lispro's duration is fixed (3-5 hours), not dose-dependent; 15-minute timing , NPH compatibility , and peakless profile are true.
You may also like to solve these questions
Ciprofloxacin increases the toxicity of theophylline by
- A. Inhibiting metabolism
- B. Decreasing excretion
- C. Decrease seizure threshold
- D. Promote absorption
Correct Answer: B
Rationale: Ciprofloxacin reduces theophylline clearance, decreasing excretion.
Isotonic normal saline (0.9%) solution is LEAST indicated in which one of the following conditions?
- A. Vomiting
- B. Hypercalcemia
- C. Body wide sodium depletion (e.g. DKA)
- D. Volume overload (e.g. liver disease)
Correct Answer: D
Rationale: Normal saline worsens volume overload in conditions like liver disease due to sodium retention.
Which of the following is considered a unit dose system?
- A. Floor stock bottle of aspirin 81 mg
- B. A prefilled Lovenox syringe
- C. One cartoon of Phenergan suppository
- D. Floor stock bottle of ibuprofen suspension
Correct Answer: B
Rationale: Examples of unit dose medications include a package that contains one tablet or capsule, a premeasured amount of a liquid drug, a prefilled syringe, or one suppository.
A patient is to receive a daily dose of 240 mg of a medication. The dose is supposed to be divided evenly so that the drug is given every 6 hours. How much of the drug should be given at each dose?
- A. 30 mg
- B. 40 mg
- C. 50 mg
- D. 60 mg
Correct Answer: D
Rationale: Because there are 24 hours in a day, giving a drug every 6 hours would mean giving the drug four times a day. Because the total daily dose is 240 mg, dividing that dose by four would mean each dose should be 60 mg.
In teaching about the use of sublingual nitroglycerine, the patient should be instructed:
- A. To swallow the tablet with a full glass of water
- B. To place one tablet under the tongue if chest pain occurs and allow it to dissolve
- C. To take one tablet every 5 minutes until the chest pain goes away
- D. That it should 'burn' when placed under the tongue or it is no longer effective
Correct Answer: B
Rationale: Sublingual nitroglycerin is placed under the tongue for rapid absorption.