Nokea
Choose the correct statement about ondansetron:
- A. It is a dopamine D2 receptor antagonist
- B. It suppresses postoperative nausea and vomiting
- C. It is the most effective antiemetic for motion sickness
- D. It is not effective by oral route
Correct Answer: B
Rationale: Ondansetron, a 5-HT3 receptor antagonist, effectively suppresses postoperative nausea and vomiting; it's less effective for motion sickness and is effective orally.
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A nurse is teaching a female client who has tobacco use disorder about Nicotine replacement therapy. Which of the following statements by the client indicates understanding of the teaching?
- A. I should avoid eating right before I chew a piece of nicotine gum.
- B. I will need to stop using the nicotine gum after 1 year.
- C. I know that nicotine gum is a safe alternative to resulting if I become pregnant.
- D. I must chew the nicotine gum quickly for about 15 minutes.
Correct Answer: A
Rationale: Avoiding food before chewing enhances nicotine absorption; gum isn't safe in pregnancy, and chewing is slow.
Which of the following is considered a unit dose system?
- A. Floor stock bottle of aspirin 81 mg
- B. A prefilled Lovenox syringe
- C. One cartoon of Phenergan suppository
- D. Floor stock bottle of ibuprofen suspension
Correct Answer: B
Rationale: Examples of unit dose medications include a package that contains one tablet or capsule, a premeasured amount of a liquid drug, a prefilled syringe, or one suppository.
Drug studies generally base the recommended adult dose of a drug needed to reach a critical concentration on what measure?
- A. A 60-year-old man
- B. An average-sized woman
- C. A 150-pound adult male
- D. An obese adult
Correct Answer: C
Rationale: Drug dosages are often standardized based on a 150-pound adult male as a common reference in pharmacological studies.
The most frequent type of drug-food interaction is food:
- A. Causing increased therapeutic drug levels
- B. Affecting the metabolism of the drug
- C. Altering the volume of distribution of drugs
- D. Affecting the gastrointestinal absorption of drugs
Correct Answer: D
Rationale: Food most commonly affects drug absorption in the GI tract by altering pH, delaying gastric emptying, or binding to drugs, impacting bioavailability.
In the liver insulin facilitates:
- A. Lypolisis
- B. Inhibit lipolysis
- C. Enhance lipoprotein lipase activity and support hydrolysis of triglycerides from lipoproteins
- D. Decrease production of glycerol phosphate and esterification of fatty acids
Correct Answer: B
Rationale: Insulin inhibits lipolysis in the liver, reducing fatty acid release.