What patient populations would the nurse expect is most likely to be prescribed a drug for an off-label use?
- A. Adolescent and middle-aged adult patients
- B. Patients with diabetes or heart disease
Correct Answer: B
Rationale: Patients with chronic conditions like diabetes or heart disease are more likely to receive off-label prescriptions due to limited standard treatment options or the need for alternative therapies when conventional drugs are ineffective. Adolescents and middle-aged adults are less likely unless specific conditions warrant it, but the document cuts off, and based on clinical context, chronic disease patients are a common focus for off-label use.
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Which of the following is not used for hyperthyroidism:
- A. Triiodthironine
- B. Mercazolil
- C. Diiodthironine
- D. Potassium iodide
Correct Answer: A
Rationale: Triiodothyronine (T3) is a thyroid hormone, not a treatment for hyperthyroidism, unlike the others.
There is enough preliminary evidence to recommend that children with autism receive which supplemental nutrient?
- A. Vitamin B1 (thiamine)
- B. Vitamin B2 (riboflavin)
- C. Calcium
- D. Omega-3 fatty acids
Correct Answer: D
Rationale: Preliminary evidence suggests omega-3 fatty acids may benefit children with autism.
While administering a medication that the nurse has researched and found to have limited effectiveness, the patient tells the nurse, I have read all about this drug and it is such a wonder drug. I'm so lucky my doctor prescribed it because I just know it will treat my problem. The nurse suspects this drug will be more effective than usual for this patient because of what effect?
- A. Cumulative effect
- B. First-pass effect
- C. Placebo effect
- D. Cross-tolerance effect
Correct Answer: C
Rationale: A drug is more likely to be effective if the patient thinks it will work than if the patient believes it will not work. This is called the placebo effect. If a drug is taken in successive doses at intervals that are shorter than recommended, or if the body is unable to eliminate a drug properly, the drug can accumulate in the body, leading to toxic levels and adverse effects. This is a cumulative effect. First-pass effect addresses the reduction of available drug when taken orally due to metabolism in the liver before the drug reaches the bloodstream. Cross-tolerance is resistance to drugs within the same class.
What would the nurse provide when preparing a patient for discharge and home medication self-administration?
- A. Personal contact information to use if the patient has questions
- B. Thorough medication teaching about drugs and the drug regimen
- C. Over-the-counter medications to use to treat potential adverse effects
- D. A sample size package of medication to take home until prescription is filled
Correct Answer: B
Rationale: The nurse is responsible for providing thorough medication teaching about drugs and the drug regimen to ensure the patient knows how to take the medication and when to notify the provider. The nurse never provides personal contact information to a patient. If adverse effects arise, the patient is taught to call the health care provider and should not self-medicate with over-the-counter drugs, which could mask serious symptoms. The nurse never dispenses medication because it must be properly labeled for home use; this is done by the pharmacy.
Ciprofloxacin increases the toxicity of theophylline by
- A. Inhibiting metabolism
- B. Decreasing excretion
- C. Decrease seizure threshold
- D. Promote absorption
Correct Answer: B
Rationale: Ciprofloxacin reduces theophylline clearance, decreasing excretion.
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