Nokea
In the liver insulin facilitates:
- A. Lypolisis
- B. Inhibit lipolysis
- C. Enhance lipoprotein lipase activity and support hydrolysis of triglycerides from lipoproteins
- D. Decrease production of glycerol phosphate and esterification of fatty acids
Correct Answer: B
Rationale: Insulin inhibits lipolysis in the liver, reducing fatty acid release.
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Which of the following is corresponding to the following statement: this drug is used for diabetes mellitus and while using there is an increased risk of pancreatitis:
- A. Miglitol
- B. Pioglitazon
- C. Exenatide
- D. Glimepiride
Correct Answer: C
Rationale: Exenatide, a GLP-1 agonist, treats diabetes and has a known risk of pancreatitis as a rare but serious side effect.
In teaching about the use of sublingual nitroglycerine, the patient should be instructed:
- A. To swallow the tablet with a full glass of water
- B. To place one tablet under the tongue if chest pain occurs and allow it to dissolve
- C. To take one tablet every 5 minutes until the chest pain goes away
- D. That it should 'burn' when placed under the tongue or it is no longer effective
Correct Answer: B
Rationale: Sublingual nitroglycerin is placed under the tongue for rapid absorption.
The most frequent type of drug-food interaction is food:
- A. Causing increased therapeutic drug levels
- B. Affecting the metabolism of the drug
- C. Altering the volume of distribution of drugs
- D. Affecting the gastrointestinal absorption of drugs
Correct Answer: D
Rationale: Food most commonly affects drug absorption in the GI tract by altering pH, delaying gastric emptying, or binding to drugs, impacting bioavailability.
Choose the correct statement about ondansetron:
- A. It is a dopamine D2 receptor antagonist
- B. It suppresses postoperative nausea and vomiting
- C. It is the most effective antiemetic for motion sickness
- D. It is not effective by oral route
Correct Answer: B
Rationale: Ondansetron, a 5-HT3 receptor antagonist, effectively suppresses postoperative nausea and vomiting; it's less effective for motion sickness and is effective orally.
Ciprofloxacin increases the toxicity of theophylline by
- A. Inhibiting metabolism
- B. Decreasing excretion
- C. Decrease seizure threshold
- D. Promote absorption
Correct Answer: B
Rationale: Ciprofloxacin reduces theophylline clearance, decreasing excretion.