The health care provider has prescribed silver sulfadiazine (Silvadene) for the client with a partial thickness burn, which has cultured positive for gram-negative bacteria. The nurse is reinforcing information to the client about the medication. Which statement made by the client indicates a lack of understanding about the treatments?
- A. The medication is an antibacterial.'
- B. The medication will help heal the burn.'
- C. The medication will permanently stain my skin.'
- D. The medication should be applied directly to the wound.'
Correct Answer: C
Rationale: Silver sulfadiazine (Silvadene) is an antibacterial that has a broad spectrum of activity against gram-negative bacteria, gram-positive bacteria, and yeast. It is applied directly to the wound to assist in healing. It does not stain the skin.
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A pharmacology student asks the instructor what an accurate description of a drug agonist is. What is the instructor's best response?
- A. A drug that reacts with a receptor site on a cell preventing a reaction with another chemical on a different receptor site
- B. A drug that interferes with the enzyme systems that act as catalyst for different chemical reactions
- C. A drug that interacts directly with receptor sites to cause the same activity that a natural chemical would cause at that site
- D. A drug that reacts with receptor sites to block normal stimulation, producing no effect
Correct Answer: C
Rationale: Agonists are drugs that produce effects similar to those produced by naturally occurring neurotransmitters, hormones, or other substances found in the body. Noncompetitive antagonists are drugs that react with some receptor sites preventing the reaction of another chemical with a different receptor site. Drug-enzyme interactions interfere with the enzyme systems that stimulate various chemical reactions.
A patient is to receive a daily dose of 240 mg of a medication. The dose is supposed to be divided evenly so that the drug is given every 6 hours. How much of the drug should be given at each dose?
- A. 30 mg
- B. 40 mg
- C. 50 mg
- D. 60 mg
Correct Answer: D
Rationale: Because there are 24 hours in a day, giving a drug every 6 hours would mean giving the drug four times a day. Because the total daily dose is 240 mg, dividing that dose by four would mean each dose should be 60 mg.
A nurse on a medical-surgical unit administers a hypnotic medication to an older adult client at 2100 . The next morning, the client is drowsy and wants to sleep instead of eating breakfast. Which of the following factors should the nurse identify as a possible reason for the client's drowsiness?
- A. Reduced cardiac function
- B. First pass effect
- C. Reduced hepatic function
- D. Increased gastric motility
Correct Answer: C
Rationale: Reduced hepatic function in older adults slows metabolism of hypnotics, prolonging drowsiness.
Beta-blockers decrease triglyceride levels and increase levels of HDL cholesterol.
- A. TRUE
- B. FALSE
Correct Answer: B
Rationale: Beta-blockers typically increase triglycerides and decrease HDL cholesterol, opposite to the statement.
Which of the following is considered a unit dose system?
- A. Floor stock bottle of aspirin 81 mg
- B. A prefilled Lovenox syringe
- C. One cartoon of Phenergan suppository
- D. Floor stock bottle of ibuprofen suspension
Correct Answer: B
Rationale: Examples of unit dose medications include a package that contains one tablet or capsule, a premeasured amount of a liquid drug, a prefilled syringe, or one suppository.
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