Long-acting beta-agonists (LTBAs) received a Black Box Warning from the U.S. Food and Drug Administration due to the:
- A. Risk of life-threatening dermatological reactions
- B. Increased incidence of cardiac events when LTBAs are used
- C. Increased risk of asthma-related deaths when LTBAs are used
- D. Risk for life-threatening alterations in electrolytes
Correct Answer: C
Rationale: The FDA Black Box Warning for LTBAs highlights increased asthma-related mortality risk, not dermatologic , cardiac , or electrolyte issues.
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A 31-year-old woman with chronic anemia presents with a deepening of her voice and a decrease in breast size.
- A. Clomiphene
- B. Hydrochlorothiazide
- C. Furosemide
- D. Nandrolone
Correct Answer: D
Rationale: Nandrolone, an anabolic steroid, causes virilization (voice deepening, breast reduction).
Valerian tea causes relaxation and can be used to help a patient fall asleep. Overdosage of valerian (more than 2.5 gm/dose) may lead to:
- A. Cardiac disturbances
- B. Central nervous system depression
- C. Respiratory depression
- D. Skin rashes
Correct Answer: A
Rationale: Valerian overdose can cause cardiac disturbances due to its sedative effects.
Which is a 5HT-receptor agonist?
- A. Ondansetron
- B. Ketanserine
- C. Sumatriptan
- D. Risperidone
Correct Answer: C
Rationale: Sumatriptan is a 5-HT1D agonist used in migraine.
While taking an angiotensin II receptor blocker (ARB), patients need to avoid certain over-the-counter drugs without first consulting the provider because:
- A. Cimetidine is metabolized by the CYP 3A4 isoenzymes
- B. Nonsteroidal anti-inflammatory drugs reduce prostaglandin levels
- C. Both 1 and 2
- D. Neither 1 nor 2
Correct Answer: B
Rationale: NSAIDs reduce prostaglandins, counteracting ARB's renal protective effects.
Monitoring for a patient being prescribed iron for iron deficiency anemia includes:
- A. Reticulocyte count 1 week after therapy is started
- B. Complete blood count every 2 weeks throughout therapy
- C. Hemoglobin level at 1 week of therapy
- D. INR weekly throughout therapy
Correct Answer: A
Rationale: Reticulocyte count at 1 week assesses iron therapy response; CBC or hemoglobin checks are later, and INR is irrelevant.
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