Milk and other foods that alkalinize the urine may:
- A. Result in basic drugs, being, reabsosibet in
- B. Increase the elimination of basic drugs in the urine
- C. Decrease the elimination of acidic drugs
- D. Not alter drug elimination due to the minimal change in urine pH
Correct Answer: C
Rationale: Alkalinizing urine increases ionization of acidic drugs, reducing their reabsorption and thus decreasing elimination.
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A patient wants to know about the possible interactions of the various drugs that he has been prescribed for an illness. The nurse explains that the drugs interact with each other and produce an effect that is greater than the sum of their separate actions. Which of the following reactions is the nurse informing about?
- A. Additive drug reaction
- B. Synergistic drug reaction
- C. Antagonistic drug reaction
- D. Toxic drug reaction
Correct Answer: B
Rationale: A synergistic drug reaction occurs when drugs interact with each other and produce a sum greater than the sum of their separate actions. An additive drug reaction occurs when the combined effect of two drugs is equal to the sum of each drug given alone. An antagonistic drug reaction occurs when one drug interferes with the action of another, causing neutralization or a decrease in the effect of one drug. Toxic drug reactions are caused when blood concentration levels exceed the therapeutic levels of a drug.
Avoid concurrent administration of exenatide with which of the following drugs?
- A. Digoxin
- B. Warfarin
- C. Lovastatin
- D. All of the above
Correct Answer: D
Rationale: Exenatide delays gastric emptying, potentially affecting absorption of digoxin , warfarin , and lovastatin .
Teaching the patient/caregiver about their medications is an important step in reducing the risk of medication errors. What is an important teaching point about medications?
- A. Speak up
- B. Store medications in a warm humid place
- C. Adjust your medication according to your weight
- D. Keep a list of your prescribed medications
Correct Answer: D
Rationale: Keeping a medication list enhances safety by ensuring all providers know current drugs, reducing error risk.
Tamoxifen is prescribed for the client with metastatic breast carcinoma. The nurse understands that the primary action of this medication is to:
- A. Increase DNA and RNA synthesis.
- B. Promote the biosynthesis of nucleic acids.
- C. Increase estrogen concentration and estrogen response.
- D. Compete with estradiol for binding to estrogen in tissues containing high concentrations of receptors.
Correct Answer: D
Rationale: Tamoxifen is an antineoplastic medication that competes with estradiol for binding to estrogen in tissues containing high concentrations of receptors. Tamoxifen is used to treat metastatic breast carcinoma in women and men. Tamoxifen is also effective in delaying the recurrence of cancer following mastectomy. Tamoxifen reduces DNA synthesis and estrogen response.
A nurse is admitting a client and completing a preassessment before administering medications. Which of the following data should the nurse include in the preassessment? (Select ONE that does not apply.)
- A. Use of herbal teas
- B. Daily fluid intake
- C. Current health status
- D. Previous surgical history
Correct Answer: B
Rationale: Herbal teas , health status , surgical history , and allergies impact medication safety; fluid intake is less critical.
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