Practice Questions for Respiratory System Related

Review Practice Questions for Respiratory System related questions and content

Myoglobin is a muscle hemoglobin which exhibits Hyperbolic oxygen dissociation curve indicating its great affinity towards Oxygen (Non-cooperative binding). The Hyperbolic nature of the curve is due to

  • A. Single polypeptide (153 amino acids) and Monomeric nature
  • B. High concentration in the muscle
  • C. Muscle protein
  • D. Quarternary structure
Correct Answer: A

Rationale: Step-by-step rationale for choice A being correct:
1. Myoglobin is composed of a single polypeptide chain with 153 amino acids, making it monomeric.
2. Being monomeric, myoglobin does not exhibit cooperative binding, leading to a hyperbolic oxygen dissociation curve.
3. The lack of multiple subunits in myoglobin results in non-cooperative binding and a hyperbolic curve.
4. The monomeric nature allows myoglobin to have a simple structure, enhancing its affinity for oxygen.
Summary of why other choices are incorrect:
B: High concentration in the muscle does not directly explain the hyperbolic curve.
C: Being a muscle protein does not inherently determine the hyperbolic nature of the oxygen dissociation curve.
D: Quaternary structure would involve multiple subunits, leading to cooperative binding and a sigmoidal oxygen dissociation curve.