Neurodegenerative diseases include the following:
- A. Niemann-Pick disease
- B. Metachromatic leukodystrophy
- C. Leigh's encephalopathy
- D. Canavan disease
Correct Answer: A
Rationale: The correct answer is A because Niemann-Pick disease is a neurodegenerative disorder. The other options (b-e) are also neurodegenerative diseases.
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The following statements are true about screening:
- A. The sensitivity of a screening test is the extent of picking up true negatives
- B. Positive predictive value is dependent on the population being screened
- C. A good screening test is always inexpensive
- D. Screening for Duchenne muscular dystrophy is not practised, mainly because of the extent of false positives in the test
Correct Answer: B
Rationale: The positive predictive value of a screening test is influenced by the prevalence of the condition in the population being screened.
Malignant mutation in hypertrophic cardiomyopathy is which of the following?
- A. Arg 403 Gln
- B. Gln 403 Arg
- C. Arg 304 Gln
- D. Gln 304 Arg
Correct Answer: A
Rationale: The Arg 403 Gln mutation is a known pathogenic mutation in hypertrophic cardiomyopathy, linked with a higher risk of sudden cardiac death.
A client who has a history of long-standing back pain treated with methadone (Dolophines), is admitted to the surgical unit following urological surgery. Which modifications in the plan of care should the nurse make for this client's pain management during the postoperative period?
- A. Consult with surgeon about increasing methadone in lieu of parenteral opioids.
- B. Use minimal parenteral opioids for surgical pain, in addition to oral methadone
- C. Maintain client's methadone, and medicate surgical pain based on pain rating
- D. Make no changes in the standard pain management for the surgery and hold methadone.
Correct Answer: C
Rationale: Maintaining the client's methadone regimen while addressing surgical pain ensures effective pain control without risking withdrawal or inadequate pain relief.
What is the definition of a giant coronary artery aneurysm in Kawasaki Disease?
- A. ≥8 mm in diameter
- B. Z score ≥10
- C. Both A and B
- D. None of the above
Correct Answer: C
Rationale: A giant coronary artery aneurysm in Kawasaki Disease is defined by either a diameter of ≥8 mm or a Z score ≥10, which indicates a significantly increased size.
Shone complex consist of the following EXCEPT
- A. coarctation of the aorta
- B. subvalvar aortic stenosis
- C. valvar aortic stenosis
- D. pulmonic stenosis
Correct Answer: D
Rationale: Pulmonic stenosis is not part of Shone complex.