Nokea
Niaspan is less likely to cause which side effect that is common to niacin?
- A. Gastrointestinal irritation
- B. Cutaneous flushing
- C. Dehydration
- D. Headaches
Correct Answer: B
Rationale: Niaspan's extended-release form reduces flushing compared to immediate-release niacin.
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Which classification does meperidine (Demerol) fall under?
- A. I
- B. II
- C. III
- D. IV
Correct Answer: B
Rationale: Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to severe psychological and physical dependence.
The nurse is caring for a patient who takes several drugs. What patient would the nurse monitor most closely because of an increased risk for adverse effects of medications?
- A. The school-aged child
- B. The obese middle-aged man
- C. The adolescent
- D. The newborn infant
Correct Answer: D
Rationale: Newborns have immature organs, increasing risk for adverse effects from multiple drugs.
Which of the following is a thiazolidinediones:
- A. Pioglitazone
- B. Exenatide
- C. Sitagliptine
- D. Chlorpropamide
Correct Answer: A
Rationale: Pioglitazone is a thiazolidinedione that enhances insulin sensitivity via PPAR-gamma.
A patient presents in the emergency department with a massive overdose of a drug. The most worrisome signs and symptoms include excessive cardiac stimulation (severe tachycardia, palpitations, angina, etc.). The EDphysician orders IV administration a -adrenergic blocker, saying (correctly) it is the only drug likely to normalize cardiac function quickly and save the patient's life. Which of the following was the most likely drug the patient overdosed on?
- A. A second-generation sulfonylurea (e.g., glipizide, glyburide)
- B. Insulin
- C. Levothyroxine
- D. Prednisone (oral glucocorticoid)
Correct Answer: C
Rationale: Levothyroxine overdose causes thyrotoxicosis, leading to cardiac overstimulation treatable with beta-blockers.
The following adverse effects are associated with niacin EXCEPT:
- A. Flushing and itching
- B. Hypercuricemia
- C. Hyperglycemia
- D. Pellagra
Correct Answer: D
Rationale: Pellagra is caused by niacin deficiency, not an adverse effect of niacin therapy.