Nonselective beta blockers and alcohol create serious drug interactions with insulin because they:
- A. Increase blood glucose levels
- B. Produce unexplained diaphoresis
- C. Interfere with the ability of the body to metabolize glucose
- D. Mask the signs and symptoms of altered glucose levels
Correct Answer: D
Rationale: Nonselective beta blockers and alcohol mask hypoglycemia symptoms (e.g., tachycardia), complicating detection.
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A patient will begin taking streptomycin as part of the medication regimen to treat tuberculosis. Before administering this medication, the nurse will review which laboratory values in the patient's medical record?
- A. Complete blood count (CBC) with differential white cell count
- B. Blood urea nitrogen (BUN) and creatinine
- C. Potassium and magnesium levels
- D. Serum fasting glucose
Correct Answer: B
Rationale: Streptomycin risks nephrotoxicity, requiring renal function (BUN, creatinine) checks; CBC or electrolytes are less critical. Streptomycin can cause significant renal toxicity.
Which of these beta-blockers is a Class III antiarrhythmic agent?
- A. Metoprolol
- B. Esmolol
- C. Sotalol
- D. Bucindolol
Correct Answer: C
Rationale: Sotalol has both beta-blocking and potassium channel-blocking (Class III) properties, prolonging the action potential.
Under new U.S. Food and Drug Administration labeling, Pregnancy Categories will be:
- A. Strengthened with a new coding such as C+ or C- to discern when a drug is more or less toxic to the fetus
- B. Changed to incorporate a pregnancy risk summary and clinical considerations on the drug label
- C. Eliminated, and replaced with a link to the National Library of Medicine TOXNET Web site for in-depth information regarding pregnancy concerns
- D. Clarified to include information such as safe dosages in each trimester of pregnancy
Correct Answer: B
Rationale: FDA replaced categories with risk summaries and clinical considerations for clearer, narrative-based guidance, effective 2015.
Human papillomavirus (HPV) vaccine (Gardasil, Cervarix):
- A. Is a live virus vaccine that provides immunity to six strains of HPV virus
- B. Has a common adverse effect of syncope within 15 minutes of giving the vaccine
- C. Should not be given to males younger than age 12 years
- D. May be given to pregnant women
Correct Answer: B
Rationale: HPV vaccine commonly causes syncope post-injection; it's not live , is approved for males 9+ , and is avoided in pregnancy .
A nurse is collecting data from a client who is taking Gemfibrozil. Which of the following assessment findings should the nurse identify as an adverse reaction to the medication?
- A. Mental status changes
- B. Tremor
- C. Jaundice
- D. Pneumonia
Correct Answer: C
Rationale: Gemfibrozil can cause hepatotoxicity, leading to jaundice .