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Osteosarcoma is the most common primary malignant bone tumor in children and adolescents; it has multiple subtypes and requires different modalities of treatment including surgery and chemotherapy. Of the following, the subtype of osteosarcoma which is treated by surgery alone is
- A. fibroblastic
- B. chondroblastic
- C. parosteal
- D. periosteal
Correct Answer: D
Rationale: Periosteal osteosarcoma is often treated with surgery alone if margins are clear.
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A client with cancer that has metastazised to the liver is started on chemotherapy- His physician has specified divided doses of the antimetabolite. The client asks why he could take the drug in divided doses. The appropriate response is:
- A. " There really is no reason your doctor just wrote the orders that way."
- B. "This schedule will reduce the side effect of the drug."
- C. "Divided doses produce greater cytotoxic effects on the diseased cells."
- D. "Because these drugs prevent cell division, they are more effective in divided doses,"
Correct Answer: D
Rationale: The correct response is D, "Because these drugs prevent cell division, they are more effective in divided doses."
A nurse is assessing a 12-month-old infant. Which statement best describes the infant's physical development a nurse should expect to find?
- A. Anterior fontanel closes by age 6 to 10 months.
- B. Binocularity is well established by age 8 months.
- C. Birth weight doubles by age 5 months and triples by age 1 year.
- D. Maternal iron stores persist during the first 12 months of life.
Correct Answer: C
Rationale: The statement that best describes the infant's physical development that a nurse should expect to find is that birth weight doubles by age 5 months and triples by age 1 year. This characteristic growth pattern is typical in the first year of life. Infants usually regain their birth weight by around 2 weeks of age, double it by about 5 months, and triple it by 1 year. This steady growth reflects the healthy development of the infant and is an important marker of overall well-being and nutrition. It is a key aspect that healthcare providers, including nurses, monitor closely to ensure the infant is thriving.
A client is diagnosed with human immunodeficiency virus (HIV). After recovering from the initial shock of the diagnosis, the client expresses a desire to learn as much as possible about HIV and acquired immunodeficiency syndrome (AIDS). When teaching the client about the immune system, the nurse states that adaptive immunity is provide by which type of white blood cell?
- A. Neutrophil
- B. Monocyte
- C. Basophil
- D. Lymphocyte
Correct Answer: D
Rationale: Lymphocytes are the type of white blood cells that provide adaptive immunity. There are two main types of lymphocytes: B cells and T cells. B cells produce antibodies that can specifically recognize and target certain pathogens (including HIV), while T cells have various functions in the immune response, such as directly killing infected cells or helping other immune cells. Adaptive immunity is characterized by the body's ability to remember specific pathogens and mount a targeted response upon subsequent exposures. In the context of HIV and AIDS, understanding the role of lymphocytes in adaptive immunity is essential for the client to comprehend how the virus affects the immune system and why immune function becomes compromised over time.
Nearly all cervical carcinomas contain human papillomavirus (HPV). Which of the following types is never associated with such malignancy?
- A. type6
- B. type 16
- C. type 18
- D. type 31
Correct Answer: A
Rationale: HPV type 6 is typically associated with low-grade lesions and genital warts, not cervical carcinoma.
All the following are compatible with the definition of obstructive sleep apnea EXCEPT
- A. episodes of prolonged upper airway obstruction
- B. repeated apnea
- C. 230% reduction in airflow
- D. 2-30% O2 desaturation
Correct Answer: D
Rationale: Oxygen desaturation of 2-30% is too low to define mild-to-moderate sleep apnea.