Nokea
Patients who are on chronic long-term proton pump inhibitor therapy require monitoring for:
- A. Iron deficiency anemia, vitamin B12 and calcium deficiency
- B. Folate and magnesium deficiency
- C. Elevated uric acid levels leading to gout
- D. Hypokalemia and hypocalcemia
Correct Answer: A
Rationale: PPIs impair absorption of iron, B12, and calcium long-term; magnesium is also a risk but less emphasized here.
You may also like to solve these questions
Which of the following is a carbapenem antibiotic?
- A. Meropenem
- B. Ceftriaxone
- C. Amoxicillin
- D. Aztreonam
Correct Answer: A
Rationale: Meropenem is a carbapenem, a broad-spectrum beta-lactam antibiotic, unlike ceftriaxone (cephalosporin) or amoxicillin (penicillin).
All are pro drugs except
- A. Sulindac
- B. Codeine
- C. Talampicillin
- D. Chlorpromazine
Correct Answer: D
Rationale: Chlorpromazine is active as is; others are prodrugs.
A group of nursing students are reviewing information about the process of drug development in the United States. The students demonstrate understanding of this process when they identify that which of the following categories are assigned by the Food and Drug Administration to newly approved drugs?Select one that does not apply
- A. Metabolite
- B. controlled substance
- C. Prescription
- D. Nonprescription
Correct Answer: A
Rationale: Once drugs are approved for use, the FDA assigns the drug to one of the following categories: prescription, nonprescription, or controlled substance. Metabolite refers to the inactive form of the drug. Noncontrolled substance is a term that is not used.
Which of the following statements about Thalidomide is INCORRECT?
- A. It is anti angiogenic
- B. It is anti inflammatory
- C. It is immunomodulatory
- D. It is mitogenic
Correct Answer: D
Rationale: Thalidomide is not mitogenic; it inhibits cell proliferation.
A nurse is caring for a patient who has recently moved from Vermont to south Florida. The patient has been on the same antihypertensive drug for 6 years and has had stable blood pressures and no side effects. Since her move, however, she reports having 'dizzy spells and weakness' and feels that the drug is no longer effective. The nurse knows that one possible reason for the change in the effectiveness of the drug could be which of the following?
- A. The impact of the placebo effect on the patient's response
- B. The accumulative effect of the drug if it has been taken for many years
- C. The impact of the warmer environment on the patient's physical state
- D. Problems with patient compliance with the drug regimen while on vacation
Correct Answer: C
Rationale: Antihypertensive drugs work to decrease the blood pressure. When a patient goes to a climate that is much warmer than usual, blood vessels dilate and the blood pressure falls. If a patient is taking an antihypertensive drug and enters a warmer climate, there is a chance that the patient's blood pressure will drop too low, resulting in dizziness and feelings of weakness. Most antihypertensives are metabolized and excreted and do not accumulate in the body. Patients must be very compliant with their drug regimen while on vacation. After several years on an antihypertensive drug, the effects of that drug are known; therefore, the placebo effect should not be an issue.