Nokea
Pharmacoeconomics is:
- A. The study of the part of the U.S. economy
- B. The study of the impact of prescription drug costs on the overall economy
- C. The analysis of the costs and consequences of any health-care-related treatment or service
- D. The analysis of the clinical efficacy of the drug
Correct Answer: C
Rationale: Pharmacoeconomics evaluates costs and outcomes of health-care interventions.
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A nurse is teaching a client who has a new prescription for Verapamil to control Hypertension. Which of the following instructions should the nurse include?
- A. Increase the amount of dietary fiber in the diet.
- B. Drink grapefruit juice daily to increase vitamin C intake.
- C. Decrease the amount of calcium in the diet.
- D. Withhold food for 1 hr after the medication is taken
Correct Answer: A
Rationale: Fiber prevents constipation, a common side effect of verapamil; grapefruit juice interacts adversely.
The patient tells the nurse about a new drug being tested to treat the disease she was diagnosed with and asks the nurse whether the doctor can prescribe a medication still in the preclinical phase of testing. What is the nurse's best response?
- A. The doctor would have to complete a great deal of paperwork to get approval to prescribe that drug.
- B. Sometimes pharmaceutical companies are looking for volunteers to test a new drug and the doctor could give them your name.
- C. Drugs in the preclinical phase of testing are only tested on animals and so would not be available to you.
- D. Drugs in the preclinical phase of testing are given only to healthy young men and so would not be available to you.
Correct Answer: C
Rationale: During the preclinical phase of testing drugs are tested on animals and are not available to patients. In phase I, the drug is tested on volunteers who are usually healthy young men. It is only in phase III studies that the drug is made available to prescribers who agree to closely monitor patients getting the medication.
antagonist is a substance that:
- A. Binds to the receptors and initiates changes in cell function, producing maximal effect
- B. Binds to the receptors and initiates changes in cell function, producing submaximal effect
- C. Interacts with plasma proteins and doesn't produce any effect
- D. Binds to the receptors without directly altering their functions
Correct Answer: D
Rationale: An antagonist binds receptors without activating them, blocking agonist effects.
AH are prodrugs except
- A. Enalapril
- B. Paracetamol
- C. Sulphamethoxazole
- D. Trimethoprim
Correct Answer: D
Rationale: Enalapril is a prodrug; paracetamol, sulphamethoxazole, and trimethoprim are active drugs.
Education of patients who are taking warfarin includes discussing their diet. Instructions include:
- A. Avoiding all vitamin K-containing foods
- B. Avoiding high-vitamin K-containing foods
- C. Increasing intake of iron-containing foods
- D. Making sure they eat 35 grams of fiber daily
Correct Answer: B
Rationale: High vitamin K foods antagonize warfarin; total avoidance is unnecessary, and iron or fiber aren't relevant.