Probiotics are recommended to be co-administered when are prescribed:
- A. Antacids
- B. Antihypertensives
- C. Antidiarrheals
- D. Antibiotics
Correct Answer: D
Rationale: Probiotics help restore gut flora disrupted by antibiotics.
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Beta blockers are prescribed for diabetics with caution because of their ability to produce hypoglycemia and block the common symptoms of it. Which of the following symptoms of hypoglycemia is not blocked by these drugs and so can be used to warn diabetics of possible decreased blood glucose?
- A. Dizziness
- B. Increased heart rate
- C. Nervousness and shakiness
- D. Diaphoresis
Correct Answer: D
Rationale: Diaphoresis (sweating) is not blocked by beta blockers and signals hypoglycemia.
When assessing a patient before starting a drug regimen, why would the nurse consider it important to assess baseline kidney function?
- A. To anticipate adverse effects of drugs
- B. To determine patient's baseline electrolyte levels
- C. To determine patient's ability to excrete the drug
- D. To determine patient's ability to metabolize the drug
Correct Answer: C
Rationale: Kidney function determines drug excretion, critical for dosing and avoiding toxicity.
Phase IV clinical trials in the United States are also known as:
- A. Human bioavailability trials
- B. Post marketing research
- C. Human safety and efficacy studies
- D. The last stage of animal trials before the human trials begin
Correct Answer: B
Rationale: Phase IV is post-marketing research , monitoring drugs after approval, unlike earlier phases or animal studies.
Sadie was prescribed betaxolol ophthalmic drops by her ophthalmologist to treat her glaucoma. Oral beta blockers should be avoided in patients who use ophthalmic beta blockers because:
- A. There may be an antagonistic reaction between the two
- B. The additive effects may include bradycardia
- C. They may potentiate each other and cause respiratory depression
- D. The additive effects may cause metabolic acidosis
Correct Answer: B
Rationale: Ophthalmic betaxolol can add to oral beta blockers, risking bradycardia; respiratory or acidosis are less likely.
The nurse uses what term to describe the drug level required to have a therapeutic effect?
- A. Critical concentration
- B. Dynamic equilibrium
- C. Selective toxicity
- D. Active transport
Correct Answer: A
Rationale: A critical concentration of a drug must be present before a reaction occurs within the cells to bring about the desired therapeutic effect. A dynamic equilibrium is obtained from absorption of a drug from the site of drug entry, distribution to the active site, metabolism in the liver, and excretion from the body to have a critical concentration. Selective toxicity is the ability of a drug to attach only to those systems found in foreign cells. Active transport is the process that uses energy to actively move a molecule across a cell membrane and is often involved in drug excretion in the kidney.
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