Endocrine System Test Questions Related

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Quinidine is a drug used for arrhythmias. One of its properties is strong postsynaptic alpha-adrenergic receptor blocking activity. What side effect would you expect as a result of this property?

  • A. Absence or at least decrease of lacrimal and mucus secretions
  • B. Dilated pupils that don’t constrict in bright light
  • C. Reduced blood pressure, hypotension
  • D. Skeletal muscle tremors
Correct Answer: C

Rationale: The correct answer is C: Reduced blood pressure, hypotension. Quinidine's strong postsynaptic alpha-adrenergic receptor blocking activity would result in decreased activation of these receptors, leading to vasodilation and reduced blood pressure, which can cause hypotension. Choice A is incorrect because lacrimal and mucus secretions are not directly affected by alpha-adrenergic receptor blocking. Choice B is incorrect as dilated pupils are more associated with alpha-1 adrenergic receptor blockade. Choice D is incorrect as skeletal muscle tremors are not a typical side effect of alpha-adrenergic receptor blocking.