Rabi is being prescribed phenytoin for seizures. Monitoring includes assessing:
- A. For phenytoin hypersensitivity syndrome 3 to 8 weeks after starting treatment
- B. For pedal edema throughout therapy
- C. Heart rate at each visit and consider altering therapy if heart rate is less than 60 bpm
- D. For vision changes, such as red-green blindness, at least annually
Correct Answer: A
Rationale: Phenytoin hypersensitivity syndrome can occur 3-8 weeks post-initiation.
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You need to administer 200 mL of a drug over 30 minutes using microdrip tubing (60 gtt/mL). What is the flow rate in drops per minute?
- A. 60 gtt/min
- B. 120 gtt/min
- C. 400 gtt/min
- D. 240 gtt/min
Correct Answer: C
Rationale: Flow rate = (200 mL 60 gtt/mL) ÷ 30 = 12,000 ÷ 30 = 400 gtt/min, matching option C.
Sally has been prescribed aspirin 320 mg per day for her atrial fibrillation. She also takes aspirin four or more times a day for arthritis pain. What are the symptoms of aspirin toxicity for which she would need to be evaluated?
- A. Tinnitus
- B. Diarrhea
- C. Hearing loss
- D. Photosensitivity
Correct Answer: A
Rationale: Tinnitus is an early sign of aspirin toxicity (salicylism); diarrhea or photosensitivity are less specific, and hearing loss is later.
All the following cross placenta except
- A. Warfarin
- B. Heparin
- C. Phenindione
- D. Morphine
Correct Answer: B
Rationale: Heparin, a large molecule, does not cross the placenta; others do.
Information technology can be a time-saving device in a busy practice if it is used wisely. One way to make it a help rather than a hindrance is to:
- A. Prioritize what is needed information and spond spending time reading 'interesting' information not central to the problem at hand
- B. Integrate professional and personal searching so that the same browser does not need to be accessed repeatedly
- C. Check e-mail frequently so that patient questions can be addressed promptly
- D. Check for viruses, spyware, and malware
Correct Answer: A
Rationale: Prioritizing relevant information saves time in a busy practice.
All the following induce hepatic enzymes except
- A. Rifampicin
- B. Phenytoin
- C. Barbiturates
- D. Tolbutamide
Correct Answer: D
Rationale: Tolbutamide does not significantly induce enzymes; others do.
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