Nokea
Regular intake of small amount of ethanol may
- A. Increase HDL level and LDL oxidation
- B. Decrease HDL level and LDL oxidation
- C. Increase HDL level and decrease LDL oxidation
- D. Decrease synthesis of VLDL
Correct Answer: C
Rationale: Moderate ethanol intake is known to increase HDL (good cholesterol) levels and reduce LDL oxidation, offering some cardiovascular benefit.
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Which statement is not correct about rosiglitazon:
- A. Enhance insulin production by pancreatic beta cells
- B. Increase senstivitiy towards insulin
- C. Increase uptake of glucose by tissues
Correct Answer: A
Rationale: Rosiglitazone increases insulin sensitivity, not insulin production, via PPAR-gamma activation.
In choosing a benzodiazepam to treat anxiety the prescriber needs to be aware of the possibility of dependence. The benzodiazepam with the greatest likelihood of rapidly developing dependence is:
- A. Chlordiazepoxide (Librium)
- B. Clonazepam (Klonopin)
- C. Alprazolam (Xanax)
- D. Oxazepam (Serax)
Correct Answer: C
Rationale: Alprazolam's short half-life increases dependence risk.
A 68-year-old patient who must take antihistamines for severe allergies is planning a vacation to Mexico. The nurse will encourage the patient to:
- A. Avoid sightseeing during the hottest part of the day
- B. Discontinue the antihistamines if he becomes extremely restless
- C. Decrease the dosage of the drugs if he experiences excessive thirst
- D. Continue taking the antihistamines even if he begins to hallucinate
Correct Answer: A
Rationale: Antihistamines can decrease sweating by blocking cholinergic receptors, placing the patient at high risk for heat stroke. Avoiding the hottest part of the day will help prevent dehydration and heat prostration. Extreme restlessness could indicate Parkinson-like syndrome not usually associated with antihistamines. Excessive thirst is characteristic of hyperglycemia, and hallucinations are associated with drugs that affect neurologic functioning. Nurses should never tell patients to decrease or discontinue a drug unless the prescriber has instructed them to do so.
Drugs that are prone to cause adverse drug effects include:
- A. Diuretics
- B. Inhaled anticholinergics
- C. Insulins
- D. Stimulants
Correct Answer: D
Rationale: Stimulants frequently cause ADRs (e.g., tachycardia), though diuretics and insulins also have risks; anticholinergics are less broad.
The following cholinesterase inhibitor is used in anaesthesia:
- A. Neostigmine
- B. Physostigmine
- C. Endrophonium
- D. Donepezil
Correct Answer: A
Rationale: Neostigmine reverses non-depolarizing neuromuscular blockers in anesthesia.