Sadie is a 72-year-old patient who takes omeprazole for her chronic GERD. Chronic long-term omeprazole use places her at increased risk for:
- A. Megaloblastic anemia
- B. Osteoporosis
- C. Hypertension
- D. Strokes
Correct Answer: B
Rationale: Chronic PPI use like omeprazole reduces calcium absorption, increasing osteoporosis risk; anemia is less direct.
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Patient teaching related to amlodipine includes:
- A. Increase calcium intake to prevent osteoporosis from a calcium blockade.
- B. Do not crush the tablet; it must be given in liquid form if the patient has trouble swallowing it.
- C. Avoid grapefruit juice as it affects the metabolism of this drug.
- D. Rise slowly from a supine position to reduce orthostatic hypotension.
Correct Answer: C
Rationale: Grapefruit juice inhibits CYP3A4, increasing amlodipine levels.
While studying for the test, the nursing student encounters the following drug: papaverine (Pavabid). What does the nursing student identify the name Pavabid as?
- A. The generic name
- B. The chemical name
- C. The brand name
- D. The chemical and generic name
Correct Answer: C
Rationale: Several clues indicate the brand name including capitalization of the first letter in the name and in parentheses. Generic names are not capitalized; chemical names are descriptions of the chemistry of the medication resulting in complicated names.
Insulin is used for:
- A. Treatment of diabetes mellitus type I only
- B. Treatment of diabetes mellitus type II only
- C. Treatment of diabetes mellitus type III and IV only
- D. Treatment of diabetes mellitus type I and II
Correct Answer: D
Rationale: Insulin is used for both type 1 (insulin-dependent) and type 2 (when other treatments fail) diabetes.
Which advantage(s) does the unit dose drug distribution system include? (Select one that does not apply.)
- A. Credit is given to the patient for unused medications.
- B. The pharmacist is able to analyze prescribed medications for each client for drug interactions and contraindications.
- C. There is less waste of medications.
- D. The time spent by nursing personnel preparing these medications is increased.
Correct Answer: D
Rationale: Because the pharmacist has a profile of all medications for each patient, he or she is able to analyze prescribed medications for each patient for drug interactions and contraindications. This is an advantage of the unit dose drug distribution system. Less waste of medications is an advantage of the unit dose drug distribution system. Because each dose is individually packaged, credit can be given to the patient for unused medications. There is increased pharmacist involvement and better use of his or her extensive drug knowledge and nursing personnel time is decreased with this method.
All are true except
- A. Acidic drugs bind to albumin & basic to acid glucoprotein
- B. All drugs have the same binding sites and mev compete for them
- C. Increased dosage will cause decrease in free drug in plasma throughout the therapeutic range
Correct Answer: D
Rationale: Acidic drugs bind albumin, basic drugs bind alpha-1-acid glycoprotein; binding sites differ, and increased dosage increases free drug levels.
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