Nokea
The following drugs are correctly paired with a clinical use EXCEPT:
- A. Tiludronate to treat Paget's disease of bone
- B. Raloxifene to prevent osteoporosis
- C. Picamycin to treat hypercalcemia
- D. Parathyroid hormone treats hypocalcemia
Correct Answer: D
Rationale: Parathyroid hormone treats osteoporosis, not hypocalcemia; calcitonin or bisphosphonates treat hypocalcemia.
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The nursing instructor observes several nursing students administer medications to their assigned patients. The instructor would stop what student from administering the medication until the error was corrected?
- A. The student checks the label on the medication against the administration record three times.
- B. The student enters the patient's room and asks the patient Are you Mr. Jones?
- C. The student checks the drug's brand name and generic name before taking it to the patient.
- D. The student documents the medication upon exiting the patient's room
Correct Answer: B
Rationale: Asking 'Are you Mr. Jones?' risks misidentification; students must verify identity with two identifiers (e.g., wristband).
The elimination of following drugs is dose dependant except
- A. Phenytoin
- B. Salicylate
- C. Theophylline
- D. Chlorpromazine
Correct Answer: D
Rationale: Chlorpromazine follows first-order kinetics; others exhibit dose-dependent (zero-order) elimination.
Which person should be treated with prophylactic antitubercular medication?
- A. A child who attends the same school with a child who has tuberculosis
- B. A nurse who is working in a hospital
- C. An individual who is HIV-positive with a negative TB skin test
- D. A patient who has close contact with someone who has tuberculosis
Correct Answer: D
Rationale: Close contact with TB warrants prophylaxis; school , hospital work , or HIV without exposure don't. Personal contact with a person having a diagnosis of tuberculosis is required to indicate prophylactic treatment with antitubercular therapy.
A 75-year-old woman with diabetes is taking an oral antidiabetic drug. One day she goes without eating for 18 \mathrm{~h}. Her serum glucose concentration is 48 \mathrm{mg} / \mathrm{dL} (hypoglycemic) upon arrival at the emergency department, where she is deemed to be in critical condition. Which of the following drugs most likely aggravated this fasting hypoglycemia?
- A. Acarbose
- B. Glyburide
- C. Metformin
- D. Pioglitazone
Correct Answer: B
Rationale: Glyburide, a sulfonylurea, can cause severe hypoglycemia, especially during fasting, due to prolonged insulin release.
Aminoglycosides lack activity against streptococci.
- A. TRUE
- B. FALSE
Correct Answer: B
Rationale: Aminoglycosides are effective against some streptococci (e.g., when combined with cell wall-active agents), though they are primarily used for gram-negative bacteria.