Sarah, a 42-year-old female, requests a prescription for an anorexiant to treat her obesity. A trial of phentermine is prescribed. Prescribing precautions include:
- A. Understanding that obesity is a contraindication to prescribing phentermine
- B. Anorexiants may cause tolerance and should only be prescribed for 6 months
- C. Patients should be monitored for postural hypotension
- D. Renal function should be monitored closely while on anorexiants
Correct Answer: C
Rationale: Phentermine can cause postural hypotension, requiring monitoring.
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You are to infuse 1,200 mL of IV fluid over 6 hours using a drop factor of 10 gtt/mL. What is the flow rate in drops per minute?
- A. 30 gtt/min
- B. 33 gtt/min
- C. 40 gtt/min
- D. 50 gtt/min
Correct Answer: B
Rationale: Flow rate = (1,200 mL 10 gtt/mL) ÷ (6 60) = 12,000 ÷ 360 = 33.33 gtt/min, rounded to 33 gtt/min.
As an antacid, sodium bicarbonate has the following disadvantages EXCEPT:
- A. It causes acid rebound
- B. In ulcer patients, it increases risk of perforation
- C. It has low acid neutralizing capacity
- D. It is contraindicated in CHF
Correct Answer: C
Rationale: Sodium bicarbonate has high acid-neutralizing capacity, but it causes acid rebound, risks perforation in ulcers due to gas production, and is contraindicated in CHF due to sodium load.
Which of the following combinations of drugs should be used in the treatment of a patient with organophosphate poisoning?
- A. Atropine and epinephrine
- B. Epinephrine and isoproterenol
- C. Norepinephrine and propranolol
- D. Atropine and pralidoxime
Correct Answer: D
Rationale: Atropine blocks muscarinic effects, and pralidoxime regenerates cholinesterase.
The average starting dose of warfarin is 5 mg daily. Higher doses of 7.5 mg daily should be considered in which patients?
- A. Pregnant women
- B. Elderly men
- C. Overweight or obese patients
- D. Patients with multiple comorbidities
Correct Answer: C
Rationale: Overweight/obese patients may need higher warfarin doses due to larger volume of distribution; pregnancy contraindicates warfarin.
Which statement is not correct regarding acarbose:
- A. Is for internal use
- B. Inhibiting alfa glucosidase
- C. Inhibits carbohydrates absorbtion in the gut
- D. Is effective for diabetes mellitus type I
Correct Answer: D
Rationale: Acarbose is primarily effective for type 2 diabetes by delaying carbohydrate absorption, not type 1, which relies on insulin deficiency.