Nokea
Which of these beta-blockers is a Class III antiarrhythmic agent?
- A. Metoprolol
- B. Esmolol
- C. Sotalol
- D. Bucindolol
Correct Answer: C
Rationale: Sotalol has both beta-blocking and potassium channel-blocking (Class III) properties, prolonging the action potential.
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Up to 21% of Asians are ultra-rapid 2D6 metabolizers, requiring:
- A. A need to monitor drugs metabolized by 2D6 for toxicity
- B. Increased dosages needed of drugs metabolized by 2D6, such as the selective serotonin reuptake inhibitors
- C. Decreased conversion of codeine to morphine by CYP 2D6
- D. The need for lowered dosages of drugs, such as beta blockers
Correct Answer: B
Rationale: Ultra-rapid 2D6 metabolizers (e.g., in Asians) need higher SSRI doses due to fast metabolism, unlike toxicity , codeine issues , or lower doses .
Which of the following statements is correct?
- A. Most drags are absorbed in ionized form
- B. Basic drags are generally bound to plasma albumin
- C. Microsomal enzymes are located in the mitochondria of hepatic cells
- D. Blood brain barrier is deficient at the chemo receptor trigger-zone
Correct Answer: D
Rationale: The chemoreceptor trigger zone has a deficient blood-brain barrier, allowing drug access; others are incorrect.
A nurse is providing teaching to a client who has a new prescription for Clonidine to assist with maintenance of abstinence from opioids. The nurse should instruct the client to monitor for which of the following adverse effects?
- A. Diarrhea
- B. Dry mouth
- C. Insomnia
- D. Hypertension
Correct Answer: B
Rationale: Clonidine commonly causes dry mouth due to its anticholinergic effects.
The Centers for Disease Control recommends all newborn infants receive prophylactic administration of ____ within 1 hour of birth.
- A. Gentamicin ophthalmic ointment
- B. Ciprofloxacin ophthalmic drops
- C. Erythromycin oral suspension
- D. Erythromycin ophthalmic ointment
Correct Answer: D
Rationale: Erythromycin ointment prevents neonatal conjunctivitis per CDC; oral isn't used.
A nurse in a provider's office is reviewing the medical record of a client who is pregnant and is at her first prenatal visit. Which of the following immunizations may the nurse administer safely to this client?
- A. Varicella vaccine
- B. Rubella vaccine
- C. Inactivated influenza vaccine
- D. Measles vaccine
Correct Answer: C
Rationale: Inactivated influenza vaccine is safe in pregnancy; live vaccines (A, B, D) are contraindicated.