Nokea
Tamoxifen is prescribed for the client with metastatic breast carcinoma. The nurse understands that the primary action of this medication is to:
- A. Increase DNA and RNA synthesis.
- B. Promote the biosynthesis of nucleic acids.
- C. Increase estrogen concentration and estrogen response.
- D. Compete with estradiol for binding to estrogen in tissues containing high concentrations of receptors.
Correct Answer: D
Rationale: Tamoxifen is an antineoplastic medication that competes with estradiol for binding to estrogen in tissues containing high concentrations of receptors. Tamoxifen is used to treat metastatic breast carcinoma in women and men. Tamoxifen is also effective in delaying the recurrence of cancer following mastectomy. Tamoxifen reduces DNA synthesis and estrogen response.
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A patient asks the nurse, What is a Drug Enforcement Agency (DEA) number? What is the nurses best response?
- A. DEA Numbers are given to physicians and pharmacists when they register with the DEA to prescribe and dispense controlled substances.
- B. Physicians must have a DEA number in order to prescribe any type of medication for patients.
- C. DEA numbers are case numbers given when someone breaks the law involving a controlled substance.
- D. DEA numbers are contact numbers to talk with someone at the DEA when questions arise about controlled substances.
Correct Answer: A
Rationale: All pharmacists and physicians must register with the DEA. They are given numbers that are required before they can dispense or prescribe controlled substances. DEA numbers are only needed when prescribing controlled substances. A DEA number is neither a case number nor a phone number.
Avoid concurrent administration of exenatide with which of the following drugs?
- A. Digoxin
- B. Warfarin
- C. Lovastatin
- D. All of the above
Correct Answer: D
Rationale: Exenatide delays gastric emptying, potentially affecting absorption of digoxin , warfarin , and lovastatin .
A nurse is teaching her patient about the use of over-the-counter (OTC) drugs. Which of the following statements best informs the patient about their safe use?
- A. OTC drugs are products that are available without prescription for self-treatment of minor complaints.'
- B. OTC drugs are considered medications and should be reported on a drug history.'
- C. OTC drugs were approved as prescription drugs but later were found to be safe without the need for a prescription.'
- D. OTC drugs need to be taken with caution. They can mask the signs and symptoms of an underlying disease and interfere with prescription drug therapy.'
Correct Answer: D
Rationale: OTC drugs are considered medications and should be reported. OTC drugs are available without a prescription, although some were first approved as prescription drugs. The most important teaching should relate to their safe use and that OTC drugs can mask symptoms of disease and interfere with prescribed drugs.
A nurse is admitting a client and completing a preassessment before administering medications. Which of the following data should the nurse include in the preassessment? (Select ONE that does not apply.)
- A. Use of herbal teas
- B. Daily fluid intake
- C. Current health status
- D. Previous surgical history
Correct Answer: B
Rationale: Herbal teas , health status , surgical history , and allergies impact medication safety; fluid intake is less critical.
Milk and other foods that alkalinize the urine may:
- A. Result in basic drugs, being, reabsosibet in
- B. Increase the elimination of basic drugs in the urine
- C. Decrease the elimination of acidic drugs
- D. Not alter drug elimination due to the minimal change in urine pH
Correct Answer: C
Rationale: Alkalinizing urine increases ionization of acidic drugs, reducing their reabsorption and thus decreasing elimination.