Nokea
The beta cells of the islets of Langerhans:
- A. are the hormone-secreting cells of the adrenal cortex.
- B. are insulin-secreting pancreatic cells.
- C. secrete releasing hormones.
- D. secrete steroids.
Correct Answer: B
Rationale: The correct answer is B because beta cells of the islets of Langerhans are specialized pancreatic cells that secrete insulin, a hormone crucial for regulating blood sugar levels. Insulin helps cells absorb glucose from the bloodstream, lowering blood sugar levels. Choice A is incorrect because the hormone-secreting cells of the adrenal cortex are called adrenal cortical cells, not beta cells. Choice C is incorrect as releasing hormones are typically secreted by the hypothalamus to stimulate the pituitary gland. Choice D is incorrect because steroids are primarily secreted by the adrenal cortex, not the beta cells of the islets of Langerhans.
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Cortisol is produced by the:
- A. adrenal cortex
- B. adrenal medulla
- C. anterior pituitary
- D. pancreas
Correct Answer: A
Rationale: The correct answer is A: adrenal cortex. Cortisol is a glucocorticoid hormone produced by the adrenal cortex. The adrenal cortex is responsible for the synthesis and secretion of cortisol in response to stress. The adrenal medulla produces catecholamines like adrenaline and noradrenaline, not cortisol. The anterior pituitary produces adrenocorticotropic hormone (ACTH), which stimulates cortisol production by the adrenal cortex. The pancreas produces insulin and glucagon, not cortisol. Therefore, the adrenal cortex is the correct choice for the production of cortisol.
Concerning Alpha blockers, which of the following is CORRECT:
- A. Phentolamine is a selective Alpha1 blocker
- B. Alpha2 blockers decrease noradrenaline release
- C. Prazosin can block Alpha1 receptor only
- D. They decrease both BP and HR
Correct Answer: C
Rationale: Rationale:
C: Prazosin can block Alpha1 receptor only.
- Prazosin is a selective Alpha1 blocker, mainly used for hypertension.
- By blocking Alpha1 receptors, it reduces vasoconstriction and lowers blood pressure.
- Prazosin does not affect Alpha2 receptors, distinguishing it from non-selective Alpha blockers.
- Correct as it accurately describes Prazosin's mechanism of action.
Incorrect:
A: Phentolamine is a non-selective Alpha blocker, affecting both Alpha1 and Alpha2 receptors.
B: Alpha2 blockers increase noradrenaline release by inhibiting the negative feedback control.
D: Alpha blockers typically decrease blood pressure, but can increase heart rate due to vasodilation.
The person with _____ is most likely to receive insulin therapy.
- A. myxedema
- B. Graves’ disease
- C. diabetes insipidus
- D. hyperglycemia
Correct Answer: D
Rationale: The correct answer is D: hyperglycemia. Hyperglycemia refers to high blood sugar levels, a hallmark of diabetes mellitus. Insulin therapy is commonly prescribed to individuals with diabetes to help regulate their blood sugar levels. Myxedema (choice A) is associated with hypothyroidism, Graves' disease (choice B) is an autoimmune disorder affecting the thyroid, and diabetes insipidus (choice C) involves the kidneys and has no direct relation to insulin therapy for diabetes. Therefore, hyperglycemia is the most appropriate condition for receiving insulin therapy.
Identify the growth factor that is released by cancer cells to create a capillary network that aids the cancer growth.
- A. macrophage colony-stimulating factor
- B. platelet derived growth factor
- C. tumor angiogenesis factor
- D. epidermal growth factor
Correct Answer: C
Rationale: The correct answer is C, tumor angiogenesis factor. Cancer cells release this growth factor to promote the formation of new blood vessels (angiogenesis) around the tumor, providing a supply of nutrients and oxygen to support their growth. This process is essential for cancer progression.
A: Macrophage colony-stimulating factor is involved in the production and differentiation of macrophages, not in angiogenesis.
B: Platelet-derived growth factor promotes cell growth and division, but it is not specifically responsible for angiogenesis in the context of cancer.
D: Epidermal growth factor is a signaling molecule that promotes cell proliferation and differentiation but is not the primary factor released by cancer cells to induce angiogenesis.
Mineralcorticoids
- A. are produced in the adrenal cortex.
- B. are steroid hormones.
- C. help regulate the homeostasis of sodium and potassium.
- D. All of the above.
Correct Answer: D
Rationale: 1. Mineralocorticoids are hormones produced in the adrenal cortex (A).
2. They are steroid hormones (B) that specifically regulate sodium and potassium homeostasis (C).
3. Therefore, the correct answer is D, as mineralocorticoids encompass all these characteristics. Other choices are incorrect as they do not fully encompass the functions and characteristics of mineralocorticoids.