Nokea
The burn client is receiving treatments of topical mafenide acetate (Sulfamylon) to the site of injury. The nurse monitors the client, knowing that which of the following indicates that a systemic effect has occurred?
- A. Hyperventilation
- B. Elevated blood pressure
- C. Local pain at the burn site
- D. Local rash at the burn site
Correct Answer: A
Rationale: Mafenide acetate is a carbonic anhydrase inhibitor and can suppress renal excretion of acid, thereby causing acidosis. Clients receiving this treatment should be monitored for signs of an acid-base imbalance (hyperventilation). If this occurs, the medication should be discontinued for 1 to 2 days. Options 3 and 4 describe local rather than systemic effects. An elevated blood pressure may be expected from the pain that occurs with a burn injury.
You may also like to solve these questions
The nurse is teaching a patient about rifampin. Which statement by the patient indicates understanding of the teaching?
- A. I should not wear soft contact lenses while taking rifampin
- B. I will need regular eye examinations while taking this drug
- C. I will report orange urine to my provider immediately
- D. I understand that renal toxicity is a common adverse effect
Correct Answer: A
Rationale: Rifampin stains fluids red-orange, risking soft lens damage; eye exams are for ethambutol, and urine color is benign. Patients taking rifampin should be warned that urine, feces, saliva, sputum, sweat, and tears may turn a harmless red-orange color.
Which one of the following is a fundamental difference between competitive and noncompetitive antagonist?
- A. Competitive and non competitive work on different receptors
- B. Competitive antagonist reduces agonist potency (increase EC50) and non competitive antagonist reduces agonist efficacy (decrease E max)
- C. There is no difference between them, they are exactly the same
- D. Non competitive antagonist causes an upward shift of the E max while competitive antagonist does the opposite
Correct Answer: B
Rationale: Competitive antagonists shift potency (EC50), while noncompetitive reduce efficacy (Emax), a key pharmacological distinction.
A nurse is assessing the patient's home medication use. After listening to the patient list current medications, the nurse asks what priority question?
- A. Do you take any generic medications?
- B. Are any of these medications orphan drugs?
- C. Are these medications safe to take during pregnancy?
- D. Do you take any over-the-counter medications?
Correct Answer: D
Rationale: It is important for the nurse to specifically question use of over-the-counter medications because patients may not consider them important. The patient is unlikely to know the meaning of orphan drugs unless they too are health care providers. Safety during pregnancy, use of a generic medication, or classification of orphan drugs are things the patient would be unable to answer but could be found in reference books if the nurse wishes to research them.
When administering a prescribed drug to a client, which action would be completely inappropriate? (Select one that does not apply.)
- A. Charting immediately on the MAR after drug administration
- B. Removing a drug from an unlabeled container
- C. Giving a drug that someone else prepared
- D. Crushing tablets or opening capsules
Correct Answer: A
Rationale: The nurse should always record immediately on the MAR after drug administration. The nurse should never remove a drug from an unlabeled container, give a drug that someone else prepared, or crush tablets or open capsules without consulting a pharmacist. The drug's unit dose wrapper should remain on until the nurse arrives at the client's bedside.
Which cytochrome is responsible for drug metabolism?
- A. P-450
- B. C-3b
- C. C-3a
- D. C-2a
Correct Answer: A
Rationale: Cytochrome P-450 enzymes in the liver are primary for drug metabolism.