The following cholinesterase inhibitor is used in anaesthesia:
- A. Neostigmine
- B. Physostigmine
- C. Endrophonium
- D. Donepezil
Correct Answer: A
Rationale: Neostigmine reverses non-depolarizing neuromuscular blockers in anesthesia.
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Which of the following statements about aminoglycosides is false?
- A. They have short half-lives
- B. They are bactericidal
- C. They exacerbate weakness in myasthenia gravis patients
- D. None of the Above
Correct Answer: D
Rationale: All statements are true: aminoglycosides have short half-lives (2-3 hours), are bactericidal, and can worsen myasthenia gravis by neuromuscular blockade.
EHRs:
- A. Are being discouraged by the Centers for Medicare and Medicaid Services due to cost issues
- B. Allow for all patient data to be centralized in one location for access by multiple providers
- C. Use macros and templates to individualize care
- D. Use standardized software to facilitate interoperability between systems
Correct Answer: B
Rationale: EHRs centralize patient data for multi-provider access, improving care coordination.
Patient education regarding prescribed medication includes:
- A. Instructions written at the high school reading level
- B. Discussion of expected adverse drug reactions
- C. How to store leftover medication such as antibiotics
- D. Verbal instructions always in English
Correct Answer: B
Rationale: Discussing adverse reactions is key to patient safety and adherence, unlike rigid reading levels , language limits , or leftover storage (C, less critical).
A pharmacology student asks the instructor what an accurate description of a drug agonist is. What is the instructors best response?
- A. A drug that reacts with a receptor site on a cell preventing a reaction with another chemical on a different receptor site
- B. A drug that interferes with the enzyme systems that act as catalyst for different chemical reactions
- C. A drug that interacts directly with receptor sites to cause the same activity that a natural chemical would cause at that site
- D. A drug that reacts with receptor sites to block normal stimulation, producing no effect
Correct Answer: C
Rationale: Agonists are drugs that produce effects similar to those produced by naturally occurring neurotransmitters, hormones, or other substances found in the body. Noncompetitive antagonists are drugs that react with some receptor sites preventing the reaction of another chemical with a different receptor site. Drug-enzyme interactions interfere with the enzyme systems that stimulate various chemical reactions.
Varicella vaccine is recommended to be given to patients who are:
- A. HIV positive with a CD4+ T-lymphocyte percentage less than 15%
- B. Taking corticosteroids (up to 2 mg/kg/day or less than 20 mg/day)
- C. Pregnant
- D. Immunocompromised
Correct Answer: B
Rationale: Varicella vaccine is safe with low-dose steroids; HIV with low CD4 , pregnancy , or immunocompromise contraindicate it.