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The mean weight of 500 college students is 70 kg and the standard deviation is 3 kg. Assuming that the weight is normally distributed, determine how many students weigh between 60 kg and 75 kg.
- A. 450
- B. 476
- C. 480
- D. 490
Correct Answer: B
Rationale: Convert to z-scores: (60-70)/3 = -3.33, (75-70)/3 = 1.67. P(-3.33 < Z ≤ 1.67) = P(Z ≤ 1.67) - P(Z ≤ -3.33) = 0.9525 - (1 - 0.9996) = 0.9521. Then, 0.9521 * 500 ≈ 476, as per the document.
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Which statement is not correct about rosiglitazon:
- A. Enhance insulin production by pancreatic beta cells
- B. Increase senstivitiy towards insulin
- C. Increase uptake of glucose by tissues
Correct Answer: A
Rationale: Rosiglitazone increases insulin sensitivity, not insulin production, via PPAR-gamma activation.
Only free drugs can act on target sites and can be eliminated.
- A. TRUE
- B. FALSE
Correct Answer: A
Rationale: True; only free (unbound) drugs can interact with target sites and be filtered/excreted, as bound drugs are pharmacologically inactive.
A nurse is providing instructions to the parent of an adolescent client who has a new prescription for Albuterol, PO. Which of the following instructions should the nurse include?
- A. You can take this medication to abort an acute asthma attack.
- B. Tremors are an adverse effect of this medication.
- C. Prolonged use of this medication can cause hyperglycemia.
- D. This medication can slow skeletal growth rate.
Correct Answer: B
Rationale: Tremors are a common side effect of albuterol due to beta-agonist stimulation.
A nurse is assessing the patient's home medication use. After listening to the patient list current medications, the nurse asks what priority question?
- A. Do you take any generic medications?
- B. Are any of these medications orphan drugs?
- C. Are these medications safe to take during pregnancy?
- D. Do you take any over-the-counter medications?
Correct Answer: D
Rationale: It is important for the nurse to specifically question use of over-the-counter medications because patients may not consider them important. The patient is unlikely to know the meaning of orphan drugs unless they too are health care providers. Safety during pregnancy, use of a generic medication, or classification of orphan drugs are things the patient would be unable to answer but could be found in reference books if the nurse wishes to research them.
Which one of the following is a fundamental difference between competitive and noncompetitive antagonist?
- A. Competitive and non competitive work on different receptors
- B. Competitive antagonist reduces agonist potency (increase EC50) and non competitive antagonist reduces agonist efficacy (decrease E max)
- C. There is no difference between them, they are exactly the same
- D. Non competitive antagonist causes an upward shift of the E max while competitive antagonist does the opposite
Correct Answer: B
Rationale: Competitive antagonists shift potency (EC50), while noncompetitive reduce efficacy (Emax), a key pharmacological distinction.