The following is the antithyroid mechanism of action of mercazolil:
- A. Inbits thyrotropic hormone production in pituitary
- B. Inhibits thyroid hormone synthesis in thyroid gland
- C. Interfere follicule cells in thyroid gland
- D. Interfere iod reaptake in thyroid gland
Correct Answer: B
Rationale: Mercazolil (methimazole) inhibits thyroid hormone synthesis by blocking thyroperoxidase activity in the thyroid.
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After teaching a group of nursing students about pharmacokinetics, the instructor determines that the teaching was successful when the students identify which of the following as the first phase?
- A. Metabolism
- B. Absorption
- C. Distribution
- D. Excretion
Correct Answer: B
Rationale: Pharmacokinetics refers to the transportation activity of drugs in the body after administration. The first component is absorption. This is followed by distribution, metabolism, and finally excretion.
Which of the following is a disadvantage of IM administration?
- A. Larger volumes can be used
- B. Can affect lab tests
- C. Painful
- D. B and C
Correct Answer: C
Rationale: Intramuscular (IM) administration is painful due to needle insertion, though larger volumes are an advantage; affecting lab tests is less specific, making C the primary disadvantage.
Cara is taking levetiracetam (Keppra) to treat seizures. Routine education for levetiracetam includes reminding her:
- A. To not abruptly discontinue levetiracetam due to risk for withdrawal seizures
- B. To wear sunscreen due to photosensitivity from levetiracetam
- C. To get an annual eye exam while on levetiracetam
- D. To report weight loss if it occurs
Correct Answer: A
Rationale: Abrupt discontinuation of levetiracetam risks withdrawal seizures.
Herbs and supplements are regulated by the U.S. Food and Drug Administration.
- A. TRUE
- B. FALSE
Correct Answer: B
Rationale: Herbs and supplements are not regulated as drugs by the FDA; they fall under dietary supplement rules.
A nursing instructor is preparing a teaching plan for a group of nursing students about pharmacology. When describing this topic, the instructor would focus the discussion on which of the following as an essential aspect?
- A. Drug name
- B. Drug class
- C. Drug action
- D. Drug source
Correct Answer: C
Rationale: Pharmacology is the study of drugs and their action on living organisms. Thus, an essential aspect of pharmacology is drug action. An understanding of the drug name, drug class, and drug source is important, but the most critical aspect related to pharmacology is how the drug acts in the body.
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