Nokea
Kelly has diarrhea and is wondering if she can take loperamide (Imodium) for the diarrhea. Loperamide:
- A. Can be given to patients of all ages, including infants and children, for viral gastroenteritis
- B. Slows gastric motility and reduces fluid and electrolyte loss from diarrhea
- C. Is the treatment of choice for the diarrhea associated with E. coli 0157
- D. May be used in pregnancy and by lactating women
Correct Answer: B
Rationale: Loperamide slows motility to reduce diarrhea; it's not for infants , E. coli 0157 (C, risks toxicity), or universally safe in pregnancy .
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Angiotensin-converting enzyme inhibitors are useful in a variety of disorders. Which of the following statements are true about both its usefulness in the disorder and the reason for its use?
- A. Stable angina because it decreases the thickening of vascular walls due to decreased modified release.
- B. Heart failure because it reduces remodeling of injured myocardial tissues.
- C. Both 1 and 2 are true and the reasons are correct.
- D. Both 1 and 2 are true but the reasons are wrong.
Correct Answer: B
Rationale: ACE inhibitors reduce myocardial remodeling in heart failure; they are not used for stable angina.
Which of the following is not hypoglicemic mechanism of action of metformin?
- A. Enhance insulin release by pancreatic beta cells
- B. Increase cell permeability of glucose and utilisation
- C. Decrease gluconeogenesis
- D. Interfere carbohydrate absorption in the gut
Correct Answer: A
Rationale: Metformin does not enhance insulin release; it improves insulin sensitivity and reduces hepatic glucose production.
A patient comes to the ER having his quadriceps muscle constantly contracted, you should give him:
- A. Norepinephrine to stimulate the sympathetic nervous system
- B. An antagonist for Norepinephrine
- C. Agonist for acetylcholine
- D. Both B and C
Correct Answer: D
Rationale: Both B and C are correct: a norepinephrine antagonist (e.g., beta-blocker) or acetylcholine agonist (e.g., to relax via parasympathetic action) could relieve muscle contraction.
A nurse is caring for a client after thyroidectomy and notes that calcium gluconate is prescribed for the client. The nurse determines that this medication has been prescribed to:
- A. Treat thyroid storm.
- B. Prevent cardiac irritability.
- C. Treat hypocalcemic tetany.
- D. Stimulate the release of parathyroid hormone.
Correct Answer: C
Rationale: Hypocalcemia can develop after thyroidectomy if the parathyroid glands are accidentally removed or injured during surgery. Manifestations develop 1 to 7 days after surgery. If the client develops numbness and tingling around the mouth, fingertips, or toes or muscle spasms or twitching, the health care provider is notified immediately. Calcium gluconate should be kept at the bedside.
L-Dopa is
- A. Converted to methyl dopa in the body
- B. Antagonised by riboflavine
- C. Antagonized by nicotinic acid
- D. Combined with carbidopa for enhanced effect
Correct Answer: D
Rationale: Carbidopa enhances L-Dopa's effect by preventing peripheral breakdown.