Nokea
Kelly has diarrhea and is wondering if she can take loperamide (Imodium) for the diarrhea. Loperamide:
- A. Can be given to patients of all ages, including infants and children, for viral gastroenteritis
- B. Slows gastric motility and reduces fluid and electrolyte loss from diarrhea
- C. Is the treatment of choice for the diarrhea associated with E. coli 0157
- D. May be used in pregnancy and by lactating women
Correct Answer: B
Rationale: Loperamide slows motility to reduce diarrhea; it's not for infants , E. coli 0157 (C, risks toxicity), or universally safe in pregnancy .
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The intangible costs of drug therapy include:
- A. Loss of wages while undergoing therapy
- B. Inconvenience, pain, and suffering incurred with therapy
- C. Cost of medical equipment in the laboratory used to monitor therapeutic drug levels
- D. Cost of prescription drug coverage, such as Medicare Part D
Correct Answer: B
Rationale: Intangible costs are non-monetary, such as pain and suffering.
Which of the following is the mechanism of action of iodides:
- A. Inhibits organification of iodine
- B. By inhibiting \mathrm{Na}+/ \mathrm{l} - simporter reduce iodine transport in thyroid gland
- C. Inhibits production of trioodthyronine form tetraiodthyronine on periphery
- D. Stimulates peroxidase
Correct Answer: A
Rationale: Iodides inhibit iodine organification, reducing thyroid hormone synthesis in high doses.
The nurse explains the Drug Enforcement Agency's (DEA's) schedule of controlled substances to the nursing assistant who asks, Do you ever get a prescription for Schedule I medications? What is the nurse's best response?
- A. Schedule I medications have no medical use so they are not prescribed.
- B. Schedule I medications have the lowest risk for abuse and do not require a prescription.
- C. Schedule I medications are only prescribed in monitored units for patient safety.
- D. Schedule I medications are found in antitussives and antidiarrheals sold over the counter.
Correct Answer: A
Rationale: Schedule I medications have no medical use and are never prescribed. Schedule V medications have the lowest risk for abuse and are found mostly in antitussives and antidiarrheals but they are not sold over the counter.
A nurse is caring for a client after thyroidectomy and notes that calcium gluconate is prescribed for the client. The nurse determines that this medication has been prescribed to:
- A. Treat thyroid storm.
- B. Prevent cardiac irritability.
- C. Treat hypocalcemic tetany.
- D. Stimulate the release of parathyroid hormone.
Correct Answer: C
Rationale: Hypocalcemia can develop after thyroidectomy if the parathyroid glands are accidentally removed or injured during surgery. Manifestations develop 1 to 7 days after surgery. If the client develops numbness and tingling around the mouth, fingertips, or toes or muscle spasms or twitching, the health care provider is notified immediately. Calcium gluconate should be kept at the bedside.
Mechanisms of transmembrane signaling are the following EXCEPT:
- A. Transmembrane receptors that bind and stimulate a protein tyrosine kinase
- B. Gene replacement by the introduction of a therapeutic gene to correct a genetic effect
- C. Ligand-gated ion channels that can be induced to open or close by binding a ligand
- D. Transmembrane receptor protein that stimulates a GTP-binding signal transducer protein (G-protein) which in turn generates an intracellular second messenger
Correct Answer: B
Rationale: Gene replacement is a therapeutic strategy, not a signaling mechanism.