Nokea
The generation time of Escherichia coli is
- A. 20 min
- B. 60 min
- C. 20 hours
- D. 24 hours
Correct Answer: A
Rationale: The correct answer is A (20 min) because Escherichia coli typically has a generation time of around 20 minutes, meaning the time it takes for a bacterial population to double. This rapid reproduction rate is a key characteristic of E. coli. Option B (60 min) is incorrect as it is longer than the usual generation time. Option C (20 hours) is too long for E. coli's generation time. Option D (24 hours) is also incorrect as it is much longer than the typical generation time of E. coli.
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Your patient is a 22-year-old man. The patient reports that two weeks after unprotected sexual contact, a small ulcer appeared on its penis. The local inguinal lymph nodes are enlarged. Dark field microscopic examination of the ulcer secretions was performed. The test reveals presence of motile, curved spirochete. The most common causative agent of the disease is:
- A. Chlamydia trachoma's
- B. Treponema pallidum
- C. Neisseria gonorrhoeae
- D. Herpes simplex virus, type 2
Correct Answer: B
Rationale: The correct answer is B: Treponema pallidum. The scenario describes symptoms of primary syphilis, which is caused by Treponema pallidum. The presence of a painless ulcer (chancre) and enlarged inguinal lymph nodes are characteristic of syphilis. Dark field microscopic examination showing motile, curved spirochetes is highly specific for Treponema pallidum.
Incorrect explanations:
A: Chlamydia trachomatis typically causes urethritis or cervicitis, not painless ulcers.
C: Neisseria gonorrhoeae causes gonorrhea, which presents with purulent discharge, not painless ulcers.
D: Herpes simplex virus type 2 causes genital herpes, leading to painful ulcers and vesicles, not painless ulcers seen in syphilis.
All the statements about Pseudomonas aeruginosa are correct, EXCEPT:
- A. It is a Gram-negative bacterium
- B. It is oxidase-positive
- C. It is non-motile and non-spore forming
- D. None of the above
Correct Answer: C
Rationale: The correct answer is C: It is non-motile and non-spore forming. Pseudomonas aeruginosa is motile due to its flagella and is non-spore forming. A is correct because it is a Gram-negative bacterium, and B is correct as it is oxidase-positive. D is incorrect because C is not true.
Which toxin is specific for ETEC:
- A. TSST-1
- B. Shiga-like toxin
- C. Erythrogenic toxin
- D. LT enterotoxin
Correct Answer: D
Rationale: The correct answer is D: LT enterotoxin. This toxin is specific for Enterotoxigenic E. coli (ETEC) and is responsible for causing diarrhea by increasing cyclic AMP levels in intestinal cells. TSST-1 (choice A) is produced by Staphylococcus aureus, not ETEC. Shiga-like toxin (choice B) is produced by Shigella and EHEC, not ETEC. Erythrogenic toxin (choice C) is produced by Streptococcus pyogenes, not ETEC. Therefore, the LT enterotoxin is the specific toxin associated with ETEC.
The bacterial component targeted by penicillin is:
- A. DNA
- B. Plasma membrane
- C. Cell wall
- D. Ribosomes
Correct Answer: C
Rationale: The correct answer is C: Cell wall. Penicillin targets the cell wall of bacteria by inhibiting the formation of peptidoglycan, a crucial component of the cell wall. This weakens the cell wall, leading to bacterial cell lysis. Choice A (DNA) is incorrect because penicillin does not directly target DNA. Choice B (Plasma membrane) is incorrect as penicillin primarily affects the cell wall, not the plasma membrane. Choice D (Ribosomes) is incorrect because penicillin does not target bacterial ribosomes, which are involved in protein synthesis.
Which of the following bacteria is responsible for causing leprosy?
- A. Mycobacterium leprae
- B. Neisseria gonorrhoeae
- C. Streptococcus pneumoniae
- D. Clostridium perfringens
Correct Answer: A
Rationale: Step 1: Mycobacterium leprae is the bacterium responsible for causing leprosy, a chronic infectious disease affecting the skin and nerves.
Step 2: Neisseria gonorrhoeae causes gonorrhea, a sexually transmitted infection.
Step 3: Streptococcus pneumoniae causes pneumonia and other respiratory infections.
Step 4: Clostridium perfringens causes gas gangrene and food poisoning.
Summary: A is correct as Mycobacterium leprae specifically causes leprosy, while B, C, and D cause different diseases unrelated to leprosy.