Nokea
The health care provider has prescribed silver sulfadiazine (Silvadene) for the client with a partial thickness burn, which has cultured positive for gram-negative bacteria. The nurse is reinforcing information to the client about the medication. Which statement made by the client indicates a lack of understanding about the treatments?
- A. The medication is an antibacterial.'
- B. The medication will help heal the burn.'
- C. The medication will permanently stain my skin.'
- D. The medication should be applied directly to the wound.'
Correct Answer: C
Rationale: Silver sulfadiazine (Silvadene) is an antibacterial that has a broad spectrum of activity against gram-negative bacteria, gram-positive bacteria, and yeast. It is applied directly to the wound to assist in healing. It does not stain the skin.
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Rifampin is a nonspecific CYP450 inducer that may:
- A. Lead to toxic levels of rifampin and must be monitored closely
- B. Cause toxic levels of drugs, such as oral contraceptives, when coadministered
- C. Induce the metabolism of drugs, such as oral contraceptives, leading to therapeutic failure
- D. Cause nonspecific changes in drug metabolism
Correct Answer: C
Rationale: Rifampin induces CYP450, speeding metabolism of drugs like oral contraceptives , reducing efficacy, not causing toxicity or nonspecificity .
Isotonic normal saline (0.9%) solution is LEAST indicated in which one of the following conditions?
- A. Vomiting
- B. Hypercalcemia
- C. Body wide sodium depletion (e.g. DKA)
- D. Volume overload (e.g. liver disease)
Correct Answer: D
Rationale: Normal saline worsens volume overload in conditions like liver disease due to sodium retention.
Influenza vaccine may be administered annually to:
- A. Patients with an egg allergy
- B. Pregnant patients
- C. Patients age 6 weeks or older
- D. Patients with acute febrile illness
Correct Answer: B
Rationale: Influenza vaccine is safe in pregnancy; egg allergy requires caution, 6 weeks is too young, and fever delays it.
Drug studies generally base the recommended adult dose of a drug needed to reach a critical concentration on what measure?
- A. A 60-year-old man
- B. An average-sized woman
- C. A 150-pound adult male
- D. An obese adult
Correct Answer: C
Rationale: Drug dosages are often standardized based on a 150-pound adult male as a common reference in pharmacological studies.
Which source contains information specific to nutritional supplements?
- A. USP Dictionary of USAN & International Drug Names
- B. Natural Medicines Comprehensive Database
- C. United States Pharmacopoeia/National Formulary (USP NF)
- D. Drug Interaction Facts
Correct Answer: C
Rationale: United States Pharmacopoeia/National Formulary contains information specific to nutritional supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug names, pronunciation guide, and possible future FDA approved drugs; it does not include nutritional supplements. Natural Medicines Comprehensive Database contains evidence-based information on herbal medicines and herbal combination products; it does not include information specific to nutritional supplements. Drug Interaction Facts contains comprehensive information on drug interaction facts; it does not include nutritional supplements.