The left supra-renal vein drains into:
- A. Inferior vena cava
- B. Inferior mesenteric vein
- C. Left renal vein
- D. Superior mesenteric vein
Correct Answer: C
Rationale: The left supra-renal vein drains into the left renal vein. This is because the left adrenal gland is located above the left kidney, and the left renal vein is responsible for draining blood from the left kidney and adjacent structures, including the left adrenal gland. Therefore, the correct answer is C.
Incorrect options:
A: The inferior vena cava receives blood from various veins in the body but not specifically from the left supra-renal vein.
B: The inferior mesenteric vein drains the large intestine and does not receive blood from the left supra-renal vein.
D: The superior mesenteric vein drains blood from the small intestine and does not receive blood from the left supra-renal vein.
In summary, the left supra-renal vein drains into the left renal vein due to their anatomical proximity, making option C the correct answer.
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What accurately demonstrates that hormones of one gland influence the function of hormones of another gland?
- A. Increased insulin levels inhibit the secretion of glucagon.
- B. Increased cortisol levels stimulate the secretion of insulin.
- C. Increased testosterone levels inhibit the release of estrogen.
- D. Increased atrial natriuretic peptide (ANP) levels inhibit the secretion of aldosterone.
Correct Answer: A
Rationale: Increased insulin levels inhibit the secretion of glucagon, demonstrating the interaction between these hormones in maintaining glucose balance.
Which hormone is most important in insulin secretion?
- A. gastrin
- B. CCK
- C. GIP
- D. secretin
Correct Answer: C
Rationale: The correct answer is C: GIP (glucose-dependent insulinotropic peptide). GIP is an incretin hormone released from the small intestine in response to glucose ingestion, stimulating insulin secretion from pancreatic beta cells. Gastrin (A), CCK (B), and secretin (D) are gastrointestinal hormones that do not directly influence insulin secretion. GIP plays a crucial role in regulating blood sugar levels by promoting insulin release, making it the most important hormone in insulin secretion.
Regarding carbohydrate metabolism:
- A. glucokinase is increased in starvation
- B. the breakdown of glycogen is called glycolysis
- C. the direct oxidative pathway involves the breakdown of glucose through triose
- D. the conversion of pyruvate to acetyl-CoA is irreversible
Correct Answer: D
Rationale: Correct Answer: D - The conversion of pyruvate to acetyl-CoA is irreversible because it is catalyzed by the enzyme pyruvate dehydrogenase. This step is a key regulatory point in carbohydrate metabolism as it commits pyruvate to enter the citric acid cycle for further energy production. Reversing this step would disrupt the normal flow of metabolic pathways.
Summary of other choices:
A: Glucokinase is not increased in starvation; it regulates glucose uptake in the liver.
B: The breakdown of glycogen is called glycogenolysis, not glycolysis which is the breakdown of glucose.
C: The direct oxidative pathway involves the breakdown of glucose through glycolysis, not triose.
Which of the following is true of the hypothalamus?
- A. Secretes releasing hormones into the portal capillaries
- B. Composed of glandular tissue
- C. Called the adenohypophysis
- D. Connected to the neurohypophysis by the portal capillaries
Correct Answer: A
Rationale: The correct answer is A because the hypothalamus secretes releasing hormones into the portal capillaries, which then travel to the anterior pituitary to regulate hormone secretion. This is known as the hypothalamic-pituitary axis. Choices B and C are incorrect because the hypothalamus is not composed of glandular tissue and it is not called the adenohypophysis. Choice D is incorrect because the connection between the hypothalamus and the neurohypophysis is via the hypothalamic-hypophyseal tract, not through the portal capillaries.
A 78-year-old male with Parkinson’s disease experiences worsening of his symptoms. He is already taking levodopa. Since the disease is characterized by degeneration of dopaminergic neurons, leading to the lack of inhibition of cholinergic neurons, the addition of which medication is likely to help alleviate the patient’s symptoms?
- A. Benztropine
- B. Reserpine
- C. Doxazosin
- D. Timolol
Correct Answer: A
Rationale: The correct answer is A: Benztropine. Benztropine is an anticholinergic medication that helps alleviate Parkinson's disease symptoms by blocking the excess activity of acetylcholine, which is increased due to the lack of dopaminergic inhibition. This leads to a rebalancing of neurotransmitters in the brain, improving motor symptoms.
Choice B: Reserpine depletes neurotransmitters including dopamine, worsening Parkinson's symptoms.
Choice C: Doxazosin is an alpha-blocker used for hypertension, not Parkinson's disease.
Choice D: Timolol is a beta-blocker used for glaucoma, not Parkinson's disease.