The main structure components of viruses are
- A. nucleic acid and proteins
- B. nucleic acids and lipids
- C. lipids and protein
- D. proteins and glycoproteins
Correct Answer: A
Rationale: The correct answer is A: nucleic acid and proteins. Viruses consist of genetic material (nucleic acid) surrounded by a protein coat. The nucleic acid carries the viral genetic information, while the proteins form the capsid that protects the genetic material. This combination is essential for the virus to infect host cells and replicate. Lipids (choice B) are not typically part of the main structure of viruses. Lipids are more commonly found in the host cell membrane. Lipids and proteins (choice C) may be present in the viral envelope but are not the main structural components. Proteins and glycoproteins (choice D) are important for viral attachment and entry into host cells but do not constitute the main structural components of viruses.
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Tuberculosis can be treated by means of combined chemotherapy that includes substances with different mechanisms of action. What antituberculous medication inhibits transcription of RNA into DNA in mycobacteria?
- A. Rifampicin
- B. Isoniazid
- C. Streptomycin
- D. Ethionamide
Correct Answer: A
Rationale: Rifampicin is the correct answer because it inhibits RNA transcription in mycobacteria by binding to the bacterial RNA polymerase. This prevents the synthesis of RNA, leading to the inhibition of protein production essential for bacterial growth.
Isoniazid inhibits mycolic acid synthesis, Streptomycin inhibits protein synthesis, and Ethionamide disrupts mycolic acid synthesis. These mechanisms are different from inhibiting RNA transcription, making them incorrect choices.
While examining the feces of a patient with diarrhea, cysts with four nuclei were found. What protozoan is most likely causing the condition?
- A. Entamoeba histolytica
- B. Lamblia
- C. Trichomonas
- D. Balantidium
Correct Answer: A
Rationale: The correct answer is A: Entamoeba histolytica. This protozoan causes amoebiasis, which presents with symptoms like diarrhea. The cysts with four nuclei found in the feces are characteristic of Entamoeba histolytica. This protozoan is known to cause invasive infection, leading to tissue destruction and ulcers in the intestines. Lamblia (choice B) typically presents with cysts containing two nuclei. Trichomonas (choice C) is a sexually transmitted parasite and does not form cysts. Balantidium (choice D) is a ciliated protozoan that does not have four nuclei in its cyst form.
Which of the following is used to test for bacterial antibiotic susceptibility?
- A. Gram stain
- B. Catalase test
- C. Kirby-Bauer disk diffusion test
- D. Endospore stain
Correct Answer: C
Rationale: The correct answer is C: Kirby-Bauer disk diffusion test. This test is used to determine the antibiotic susceptibility of bacteria by measuring the zone of inhibition around antibiotic-soaked paper disks. It helps identify which antibiotics are effective against the bacteria being tested. This test is crucial in guiding antibiotic treatment decisions.
A: Gram stain is used to classify bacteria based on their cell wall composition and morphology, not for antibiotic susceptibility testing.
B: Catalase test is used to differentiate between catalase-positive and catalase-negative bacteria, not for antibiotic susceptibility testing.
D: Endospore stain is used to detect the presence of endospores in bacteria, not for antibiotic susceptibility testing.
Which of the following bacteria are unable to synthesize ATP?
- A. Chlamydia
- B. Enterococci
- C. Rickettsia
- D. Staphylococci
Correct Answer: A
Rationale: The correct answer is A: Chlamydia. Chlamydia lacks the essential enzymes for ATP synthesis and relies on host cell ATP. Enterococci, Rickettsia, and Staphylococci possess the necessary enzymes for ATP synthesis through cellular respiration. Chlamydia's inability to synthesize ATP makes it dependent on the host cell for energy production, distinguishing it from the other bacteria listed.
The virus most commonly transmitted during pregnancy is:
- A. cytomegalovirus
- B. HIV
- C. herpes simplex virus
- D. Epstein-Barr virus
Correct Answer: A
Rationale: The correct answer is A: cytomegalovirus. CMV is the most common virus transmitted during pregnancy, leading to potential serious complications for the fetus. It can cause birth defects, hearing loss, and developmental delays. CMV is commonly spread through bodily fluids. HIV (B) can also be transmitted during pregnancy but is less common. Herpes simplex virus (C) can be transmitted but typically results in localized infection. Epstein-Barr virus (D) is not commonly transmitted during pregnancy.