The major factor in terminating the action of ethanol is
- A. Biotransformation
- B. Excretion through lungs
- C. Excretion unchanged in urine
- D. Excretion in feces
Correct Answer: A
Rationale: Ethanol is primarily metabolized by the liver (biotransformation) via alcohol dehydrogenase.
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Which drug(s) would be considered to be in the category Schedule II? (Select all that apply.)
- A. Marijuana
- B. Morphine
- C. Amphetamines
- D. Fiorinal
Correct Answer: C
Rationale: Percodan and amphetamines are Schedule II drugs with high abuse potential. Marijuana is Schedule I, Fiorinal is Schedule III.
The Combination of amoxycillin + clavulanic acid is used because
- A. It broadens the spectrum of amoxycillin
- B. It decreases the side effect of amoxycillin
- C. It decreases the toxicity of clavulanic acid
- D. It increases the oral bio availability of amoxycillin
Correct Answer: A
Rationale: Clavulanic acid inhibits beta-lactamases, broadening amoxicillin's spectrum.
The patient is prescribed a medication that was just placed in Phase IV study. The patient tells the nurse, This medication is too expensive. Could the doctor order a generic form of this medication? What is the nurses most accurate response?
- A. Medications are not produced in generic form until the patent expires, which normally takes several years.
- B. You can request the generic form but the binder used may make the drug less effective for this medication.
- C. The generic form of the medication would not be any less expensive because this is a relatively new medication.
- D. Generic medications are lower quality drugs and that would mean you would not be getting the best treatment available.
Correct Answer: A
Rationale: When a new drug enters the market, it is given a time-limited patent; generic forms of the medication cannot be produced until the patent expires. Because no generic version of this drug will exist because it is so new, it is impossible to predict what binder will be used or what the cost would be.
Besides osteoporosis, IV bisphosphonates are also indicated for:
- A. Paget's Disease
- B. Early osteopenia
- C. Renal cancer
- D. Early closure of cranial sutures
Correct Answer: A
Rationale: IV bisphosphonates treat Paget's disease by reducing bone turnover; osteopenia uses oral forms typically.
Which of the following statements best defines how a chemical becomes a drug?
- A. A chemical must have a proven therapeutic value or efficacy without severe toxicity or damaging properties to become a drug.
- B. A chemical becomes a drug when it is introduced into the body to cause a change.
- C. A chemical is considered a drug when the Food and Drug Administration (FDA) approves its release to be marketed.
- D. A chemical must have demonstrated therapeutic value to become a drug.
Correct Answer: A
Rationale: A chemical must undergo a series of tests to determine its therapeutic value and efficacy without severe toxicity or damaging properties before it is termed a drug. Test results are reported to the FDA, which may or may not give approval.